Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06314477

Effect of CPAP Treatment in Patients With Severe Uncontrolled Asthma: The ASTHMA-SLEEP Trial

Led by Hospital Clinic of Barcelona · Updated on 2025-12-11

138

Participants Needed

1

Research Sites

152 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of the study is to evaluate the impact of CPAP treatment on asthma control in patients with severe uncontrolled asthma and obstructive sleep apnea (OSA)

CONDITIONS

Official Title

Effect of CPAP Treatment in Patients With Severe Uncontrolled Asthma: The ASTHMA-SLEEP Trial

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 18 years
  • Diagnosis of severe uncontrolled asthma according to Spanish Asthma Management Guide (GEMA) or Global Initiative for Asthma (GINA) criteria
  • No hospitalizations in the month before study inclusion
  • Apnea-hypopnea index of 15 or higher
  • Epworth Sleepiness Scale score of 10 or less
  • Signed informed consent obtained
Not Eligible

You will not qualify if you...

  • Previous treatment with CPAP
  • Central sleep apnea or Cheyne-Stokes respiration
  • Other sleep disorders such as narcolepsy, restless leg syndrome, or chronic insomnia
  • Resistant hypertension
  • Active smoking
  • Unstable medical conditions or medications that may affect asthma control
  • Pregnancy
  • Life expectancy less than 1 year
  • Any medical or social reason that may reduce CPAP compliance

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital Clinic Barcelona

Barcelona, Spain, Spain, 08036

Actively Recruiting

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Research Team

M

Mireia Dalmases, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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