Actively Recruiting

Early Phase 1
Age: 18Years +
All Genders
Healthy Volunteers
NCT07086482

Effect of Cyanoacrylate Tissue Adhesive Versus Collagen Sponge on Palatal Donor Site Healing

Led by Beirut Arab University · Updated on 2025-08-17

22

Participants Needed

1

Research Sites

37 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if the use of cyanoacrylate glue (PeriAcryl) is effective in healing of the palatal donor site in adults requiring a free gingival graft. The main question\[s\] it aims to answer \[is/are\]: Does PeriAcryl accelerate the palatal tissue healing compared with the use of collagen sponge? Does PeriAcryl usage leave the patients more satisfied? Researcher will compare the outcomes of participants treated with PeriAcryl to those treated with collagen sponge to see if PeriAcryl accelerated the healing process of palatal tissues and led to fewer postoperative complications. Participants will: * be assigned to a study group using PeriAcryl or control group using Collagen sponge. * be followed-up to monitor healing and gather clinical information.

CONDITIONS

Official Title

Effect of Cyanoacrylate Tissue Adhesive Versus Collagen Sponge on Palatal Donor Site Healing

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Low to moderate anesthetic risk (ASA I-II)
  • No restriction on ethnicity or gender
  • Patients needing a free gingival graft from the palate for periodontal plastic surgery
  • Clinically healthy gums after initial therapy
  • Full-mouth plaque index scores of 0 or 1
  • Bleeding scores less than 15%
Not Eligible

You will not qualify if you...

  • Smoking more than 10 cigarettes per day
  • Any bleeding or clotting disorders
  • Presence of systemic diseases
  • Use of medications that affect gum tissues
  • Pregnancy or breastfeeding
  • Allergies to prescribed medications during treatment
  • Mental health conditions affecting cooperation (e.g., dementia, psychosis)
  • Excessive gag reflex

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Beirut Arab University

Beirut, Lebanon

Actively Recruiting

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Research Team

D

Dania EL Rostom, MSc Oral and Dental Surgery

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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