Daily Mixed Spice Capsules to Support Memory in Adults Aged 50 to 80 with Mild Age-Related Cognitive Decline

What this Trial Is About

The aging process involves many changes in the brain that lead to a gradual decline in memory and thinking skills. Researchers are investigating whether a mixture of spices known for potential memory benefits can better support brain health and slow age-related cognitive decline compared to a single spice. This pilot study includes 50 adults aged 50 to 80 years who have typical mild cognitive decline but do not have dementia or major brain disorders. Participants will be randomly assigned to one of two groups one taking 4.00 g capsules daily containing a spice mixture turmeric, cinnamon, oregano, black pepper, sage, and thyme, and the other taking 4.00 g maltodextrin placebo capsules. The treatment lasts for 3 months, followed by an additional 3 months to assess if the effects are sustained. The study aims to evaluate the impact of the spice mixture on memory, as well as its antioxidant and anti-inflammatory effects. During the study, participants will undergo assessments of cognition, fatigue, mood, body weight and composition, sleep quality, diet, and quality of life. These evaluations will occur over 6 months to compare changes between the spice and placebo groups. The research team will closely monitor participants for any side effects and overall health to provide new information on dietary spice use to preserve cognitive function in aging adults.

Effect of Daily Mixed Spice Consumption on Memory Function