Randomized Trial Comparing a DASH-Style Diet and Western-Style Diet to Reduce Kidney Stone Risk

What this Trial Is About

Researchers are investigating how a healthy diet might affect risk factors for kidney stone disease KSD. This trial compares the effects of a Dietary Approaches to Stop Hypertension DASH-style diet versus a Western-style diet on urinary stone risk parameters. The goal is to understand if the DASH diet can improve measures related to kidney stones and to create a foundation for future dietary studies in this area. Participants will be randomly assigned to one of two diet groups for one week. One group will follow a DASH-style diet rich in fruits, vegetables, low-fat dairy, whole grains, poultry, fish, and nuts, while limiting red meat, sweets, and sugary drinks. The other group will follow a Western-style diet with higher amounts of red meat, sweets, processed starches, and seed oils, and lower intake of fruits, vegetables, and low-fat dairy. All meals will be provided by the Bionutrition Unit. During the study, participants will complete 24-hour urine collections to measure key urinary factors related to kidney stone risk, including calcium oxalate supersaturation. Researchers will compare these outcomes between the two diet groups on days 6 and 7 of the diet period. The study includes monitoring safety and adherence, and participants will be involved for the duration of the one-week diet intervention.

Effect of a DASH-Style Diet on Urinary Risk Factors for Kidney Stone Disease