Studying How Degenerative Spondylolisthesis Affects Outcomes After Unilateral Biportal Endoscopy Surgery for Lumbar Spinal Stenosis in Adults Aged 50 to 80

What this Trial Is About

Researchers are studying the impact of degenerative spondylolisthesis on the results of unilateral biportal endoscopy surgery for lumbar spinal stenosis. This prospective cohort trial is conducted at a single center and aims to provide stronger evidence on how the presence of degenerative spondylolisthesis affects clinical outcomes for patients undergoing this procedure. The study focuses on adults aged 50 to 80 years with lumbar spinal stenosis and compares those with and without degenerative spondylolisthesis. Participants are divided into two groups based on their condition one group includes patients with lumbar spinal stenosis combined with degenerative spondylolisthesis of Meyerding grade I, and the other group includes patients with lumbar spinal stenosis only. Both groups will undergo unilateral biportal endoscopy treatment. The study monitors patients from enrollment and follows them for 2 years to assess various clinical and imaging outcomes. Throughout the study, participants will undergo assessments including the Oswestry Disability Index ODI, X-rays, CT scans, and MRI from enrollment through the 2-year follow-up. Additional measures include surgical complications, pain scores for lower back and leg pain, operative time, blood loss, hospital stay duration, and various blood tests within 3 days after surgery. Researchers will track improvements in pain, function, and disability scores to evaluate the surgerys impact over time.

Effect of Degenerative Spondylolisthesis on the Clinical Outcome of Unilateral Biportal Endoscopy for Lumbar Spinal Stenosis: Study Protocol