Actively Recruiting
The Effect of Dexamethasone Administration Route and Local Anesthetic Concentration on Pain, Inflammatory Response, and Neuromonitoring in Children Undergoing Scoliosis Correction
Led by Poznan University of Medical Sciences · Updated on 2025-03-24
60
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Scoliosis correction surgery in children is a complex procedure with significant risks, including postoperative pain, inflammatory response, and potential neurological complications. Effective pain control and minimizing inflammation are critical for faster recovery and improved patient outcomes. Dexamethasone is commonly used as an adjuvant in regional anesthesia due to its anti-inflammatory effects and ability to prolong analgesia. However, limited research exists on the optimal route of dexamethasone administration (intravenous vs. perineural) and the best local anesthetic concentration for pain management, inflammatory response, and neuromonitoring during surgery. This study aims to compare the effects of different dexamethasone administration routes and local anesthetic concentrations on postoperative pain, inflammation (NLR, PLR), and neuromonitoring in pediatric scoliosis surgery. Results may improve regional anesthesia protocols, enhance patient safety, and offer valuable insights for clinical practice.
CONDITIONS
Official Title
The Effect of Dexamethasone Administration Route and Local Anesthetic Concentration on Pain, Inflammatory Response, and Neuromonitoring in Children Undergoing Scoliosis Correction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children older than 10 and younger than 18 years
- Scheduled for idiopathic scoliosis surgery
You will not qualify if you...
- Infection at the site of the regional block
- Blood clotting (coagulation) disorders
- Immunodeficiency
- American Society of Anesthesiologists (ASA) physical status of IV or higher
- History of regular steroid medication
AI-Screening
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Trial Site Locations
Total: 1 location
1
Poznan University of Medical Sciences
Poznan, Poland, 60-701
Actively Recruiting
Research Team
M
Malgorzata Reysner, M.D. Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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