Actively Recruiting
Effect of Dexamethasone on Labour Induction in Term Pregnancies
Led by Cairo University · Updated on 2025-08-07
150
Participants Needed
1
Research Sites
19 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of the study is to assess the effect of dexamethasone on labour induction in term pregnancies. Primary outcome: The interval between initiation of induction and beginning of the active phase of labour. Secondary outcomes: * Duration of active phase of labour (starting with cervical dilatation of 4-5 cm up to full cervical dilatation). * Duration of second stage of labour * Mode of delivery. * Fetal outcome. Group A: Will receive one dose of IM dexamethasone sodium phosphate 8 mg (2 mL). Group B: Will receive vaginal misoprostol 25 μg tablets every 6 h, up to 4 tablets, for a maximum duration of 24 h. Group C: Will receive one dose of IM dexamethasone sodium phosphate 8mg (2mL) with the first dose of vaginal misoprostol 25 μg tablets that will be given every 6 h, up to 4 tablets, for a maximum duration of 24 h.
CONDITIONS
Official Title
Effect of Dexamethasone on Labour Induction in Term Pregnancies
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age > 18 years
- Nulliparous (first pregnancy)
- Baby in vertex (head-down) position
- Single pregnancy (no multiples)
- Gestational age at least 39 weeks based on last menstrual period or early ultrasound
- No reason to avoid vaginal delivery
You will not qualify if you...
- Need for cesarean section (e.g., placenta previa, growth problems, non-vertex position, previous cesarean)
- Maternal medical problems like diabetes or severe pre-eclampsia
- Preterm labor or early rupture of membranes
- Gestational age less than 39 weeks
- Baby estimated to weigh more than 4 kg (macrosomia)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Cairo University Hospital (Kasr Al Ainy)
Cairo, Manial, Egypt, 11562
Actively Recruiting
Research Team
A
Abdelfatah M Eldesouky, MD, MRCOG
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
3
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