Actively Recruiting

Phase 4
Age: 65Years - 85Years
All Genders
Healthy Volunteers
NCT06819436

Effect of Dexamethasone on Post-spinal Hypotension

Led by Shaheed Mohtarma Benazir Bhutto Institue of Trauma · Updated on 2025-02-11

170

Participants Needed

1

Research Sites

12 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if intravenous dexamethasone is effective for prevention of post spinal hypotension in geriatric population undergoing orthopedic surgeries. The main question aim to answer is: Does intravenous dexamethasone in participants undergoing orthopedic procedures of lower limb under spinal anesthesia prevents post spinal hypotension? Researchers are comparing two groups of participants * Participants in (Dexamethasone Group) Group D are receiving intravenous dexamethasone 8mg preoperatively * Participants in (Placebo Group) Group P are receiving placebo preoperatively.

CONDITIONS

Official Title

Effect of Dexamethasone on Post-spinal Hypotension

Who Can Participate

Age: 65Years - 85Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients undergoing orthopedic surgery using spinal anesthesia
  • American Society of Anesthesiologists (ASA) physical status classification 1 or 2
  • Age between 65 and 85 years
Not Eligible

You will not qualify if you...

  • History of cardiac arrhythmias
  • History of acute coronary syndrome
  • History of polytrauma
  • Contraindications to spinal anesthesia such as coagulopathy, thrombocytopenia, or allergy to local anesthetic agents
  • Current use of steroids or serotonin-related medications such as selective serotonin reuptake inhibitors

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Shaheed Mohtarma Benazir Bhutto Institute of Trauma

Karachi, Sindh, Pakistan

Actively Recruiting

Loading map...

Research Team

S

Sidra Javed, MBBS, FCPS, Pain fellow

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Effect of Dexamethasone on Post-spinal Hypotension | DecenTrialz