Study of Intravenous Dexamethasone to Prevent Low Blood Pressure After Spinal Anesthesia in Older Adults Having Orthopedic Surgery

What this Trial Is About

This trial investigates whether intravenous dexamethasone can prevent low blood pressure after spinal anesthesia in older adults having orthopedic surgeries on their lower limbs. Researchers aim to see if giving dexamethasone before surgery reduces post-spinal hypotension compared to a placebo. The study focuses on geriatric patients aged 65 to 85 years undergoing these procedures. Participants are randomly assigned to one of two groups. One group receives an 8 mg dose of intravenous dexamethasone about 20 minutes before spinal anesthesia. The other group receives a placebo intravenously at the same time before the spinal anesthesia. This is a phase 4, single-blind, randomized study conducted at a tertiary care hospital. During the trial, participants blood pressure is monitored from enrollment until 30 minutes after spinal anesthesia to assess the occurrence of hypotension. Researchers will compare the effects of dexamethasone versus placebo on this outcome. The total participation duration includes preoperative administration and monitoring immediately after spinal anesthesia. Safety and other assessments are performed as part of routine care during this period.

Effect of Dexamethasone on Post-spinal Hypotension