Actively Recruiting
The Effect of Dexamethasone Submucosal Injection After Surgical Extraction of Lower Impacted Third Molars on Trismus and Edema
Led by King Abdulaziz University · Updated on 2025-05-01
66
Participants Needed
1
Research Sites
73 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical trial aims to investigate whether dexamethasone decreases edema and trismus in adults undergoing lower third molar surgical extraction. The main question it aims to answer is: Does dexamethasone submucosal injection have a positive impact on trismus and edema after third molar surgery compared to conventional postoperative prescription? Participants will: * Be administered with dexamethasone submucosal injection or a placebo after the surgery. * Visit the clinic three times the week after the extraction for follow-up.
CONDITIONS
Official Title
The Effect of Dexamethasone Submucosal Injection After Surgical Extraction of Lower Impacted Third Molars on Trismus and Edema
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with impacted lower third molars requiring surgical extraction.
- Adults over the age of 18 years old.
- American Society of Anaesthesiologists (ASA) physical status classification 1 or 2.
You will not qualify if you...
- Patients with preoperative intraoral or extraoral swelling.
- Patients requiring simple extraction (Class I group A according to Pell and Gregory classification).
- Patients with uncontrolled systemic diseases such as uncontrolled diabetes.
- Patients who are allergic to corticosteroids.
- Patients contraindicated for corticosteroid use, including uncontrolled diabetic and osteoporotic patients.
- Patients needing extraction of additional teeth during the same visit.
AI-Screening
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Trial Site Locations
Total: 1 location
1
King Abdulaziz University, Faculty of Dentistry
Jeddah, Mecca Region, Saudi Arabia
Actively Recruiting
Research Team
L
Lojain Bassyoni, BDS, MSc, FRCDC
CONTACT
R
Razan Baabdullah, BDS, MSc, FRCDC
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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