Actively Recruiting

Phase Not Applicable
Age: 19Years +
All Genders
NCT07066605

The Effect of Dexmedetomidine on Agitation During Weaning From Mechanical Ventilation

Led by Sohag University · Updated on 2025-07-15

62

Participants Needed

1

Research Sites

28 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate the effect of dexmedetomidine on the level of agitation during the weaning process from mechanical ventilation in critically ill patients.

CONDITIONS

Official Title

The Effect of Dexmedetomidine on Agitation During Weaning From Mechanical Ventilation

Who Can Participate

Age: 19Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult ICU patients 18 years or older
  • On mechanical ventilation for at least 24 hours
  • Clinically ready for weaning from mechanical ventilation
  • Agitation score RASS of +1 or higher during spontaneous breathing trial
  • Intubated for at least 4 days and up to 2 weeks
Not Eligible

You will not qualify if you...

  • Known hypersensitivity to dexmedetomidine
  • Hemodynamic instability with heart rate below 50 beats per minute or mean arterial pressure below 60 mmHg
  • Neurological impairment affecting consciousness level
  • Pregnancy or currently breastfeeding

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sohag University Hospital

Sohag, Egypt

Actively Recruiting

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Research Team

D

Dalia A Hussein, Resident

CONTACT

A

Al-haddad A Mousa, Professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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