Actively Recruiting
Effect of Different Centrifuge Values on Saliva High Sensitive C-Reactive Protein (Hs-CRP) Levels in Individuals With Different Smoking Amounts
Led by Izmir Katip Celebi University · Updated on 2024-12-20
90
Participants Needed
1
Research Sites
33 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study; In periodontally healthy individuals, high sensitive c-reactive protein (hs-CRP) levels of non-smokers, smokers of less than 10 cigarettes per day and smokers of more than 10 cigarettes per day were measured at 15 rpm-10 min, 10 centrifuge values, which are frequently used in saliva studies. To determine the levels in saliva samples as a result of rpm-10 min and 10 rpm 6 min centrifugations and to determine the values at which a cytokine of this molecular weight should be centrifuged and to examine the possible correlation between these values and the clinical parameters of the amount of smoking. Materials and Methods: saliva samples were collected from 90 systemically healthy individuals who were non-smokers (N, n=30), light smokers \<10 cigarettes per day (L, n=30) and heavy smokers \>10 cigarettes per day (H, n=20). samples were taken. Full-mouth clinical periodontal measurements, including probing depth (PD), clinical attachment level (CAL), bleeding on probing (BOP), gingival index (GI), and plaque index (PI), were also recorded. Enzyme-linked immunosorbent assay (ELISA) was used to determine hs-CRP levels in biological samples.
CONDITIONS
Official Title
Effect of Different Centrifuge Values on Saliva High Sensitive C-Reactive Protein (Hs-CRP) Levels in Individuals With Different Smoking Amounts
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Systemically healthy
- Periodontally clinically healthy
- At least 20 permanent teeth in the mouth
- No continuous medication use
- No use of antibiotics, anti-inflammatory, or systemic corticosteroid drugs in the last 6 months
- Not pregnant or breastfeeding
- No periodontal treatment in the last 6 months
- Non-smoker: does not smoke tobacco
- Light smoker: smokes less than 10 cigarettes per day
- Heavy smoker: smokes more than 10 cigarettes per day
You will not qualify if you...
- Any oral or systemic disease
- Regular use of systemic medication
- Pregnant or breastfeeding
- Received periodontal treatment within the last 6 months
- Used antibiotics, anti-inflammatory, or systemic corticosteroid medication in the last 6 months
- Has periodontal disease
AI-Screening
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Trial Site Locations
Total: 1 location
1
Izmir Katip Çelebi University Department of Periodontology
Izmir, Çiğli, Turkey (Türkiye), 35640
Actively Recruiting
Research Team
E
Ece Özer
CONTACT
M
Mehmet Sağlam
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
3
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