Actively Recruiting

Phase Not Applicable
Age: 1Year - 6Years
All Genders
NCT07450495

Effect of Different Concentrations of Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Surgery

Led by Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong · Updated on 2026-03-04

80

Participants Needed

1

Research Sites

57 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This randomized controlled trial aims to compare the effectiveness and safety of 6% versus 8% sevoflurane inhalation induction in pediatric patients undergoing minor ophthalmic surgery. The primary outcome is emergence agitation assessed using the Pediatric Anesthesia Emergence Delirium (PAED) scale. Secondary outcomes include hemodynamic parameters, induction time, recovery time, and adverse events.

CONDITIONS

Official Title

Effect of Different Concentrations of Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Surgery

Who Can Participate

Age: 1Year - 6Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children aged 1 to 6 years (12-72 months)
  • Scheduled to undergo minor ophthalmic surgery (e.g., chalazion excision) under general anesthesia
  • American Society of Anesthesiologists (ASA) physical status I
  • Assessed as suitable for inhalation anesthesia by anesthesiologists
  • Written informed consent obtained from parents or legal guardians
Not Eligible

You will not qualify if you...

  • ASA physical status II or higher
  • Known hepatic or renal dysfunction
  • Congenital heart disease
  • History of malignant hyperthermia
  • Known allergy to sevoflurane
  • History of asthma or severe respiratory disease
  • Upper respiratory tract infection within the past 4 weeks
  • Anticipated difficult airway
  • Refusal of participation by parents or legal guardians

AI-Screening

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Trial Site Locations

Total: 1 location

1

Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong

Shantou, Guangdong, China, 515041

Actively Recruiting

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Research Team

L

Laiwen Lv, MSc.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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