Study on the Effect of Different Deproteinizing Agents on Success of Fissure Sealants in Childrens Primary Teeth

What this Trial Is About

Researchers are studying how different deproteinizing agents affect the success of fissure sealants applied to primary teeth. This research focuses on preventing or stopping early caries tooth decay on high-risk tooth surfaces using a non-invasive method. The study compares traditional sodium hypochlorite, known for improving adhesion but with some drawbacks, to hypochlorous acid, a newer agent believed to be gentler and effective with antimicrobial properties. The study involves two treatment groups where one group receives sodium hypochlorite and the other receives hypochlorous acid for enamel deproteinization before fissure sealant application. Both agents work by removing organic material from the tooth surface to improve sealant adhesion. The study is designed as a randomized, single-blind clinical trial in a split-mouth format, meaning each participant will receive both treatments on different teeth for comparison. Participants will be monitored at 3, 6, 12, and 24 months after sealant application. During these visits, researchers will evaluate the sealants success using the Modified Simonsen Criteria and assess the integrity of the sealant edges. The study includes children aged 4 to 6 years who meet specific dental and behavioral criteria. The total participation period spans two years to observe the long-term effects of the treatments on the sealants.

The Effect of Different Deproteinizing Agents on the Clinical Success of Fissure Sealants in Primary Teeth