Actively Recruiting

Phase Not Applicable
Age: 18Years - 49Years
All Genders
Healthy Volunteers
NCT04990024

The Effect of Different Diets on Arterial Stiffness in Obese Patients on Semaglutide

Led by American University of Beirut Medical Center · Updated on 2024-08-06

60

Participants Needed

1

Research Sites

219 weeks

Total Duration

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AI-Summary

What this Trial Is About

In patients initiating Semaglutide for weight management, the objective is to compare the effect of the Mediterranean diet and the high protein/low carbohydrate (HP/LC) diet CV parameters, namely arterial stiffness, measured by carotid-femoral pulse wave velocity (cfPWV), and visceral adipose tissue, in addition to other metabolic indicators.

CONDITIONS

Official Title

The Effect of Different Diets on Arterial Stiffness in Obese Patients on Semaglutide

Who Can Participate

Age: 18Years - 49Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Men and premenopausal women, 18-49 years, with obesity defined as BMI  30 kg/m2
  • Starting Semaglutide treatment for weight management within 1-4 weeks, as advised by their physician
  • Able to commit to trial visits over 6 months
Not Eligible

You will not qualify if you...

  • Pregnant women
  • Taking or having taken other weight loss drugs in the past 6 months
  • History of metabolic weight loss surgery
  • Known diabetes (HbA1c  6.5% at screening)
  • Uncontrolled hypertension
  • Uncontrolled cardiac, pulmonary, renal, or liver diseases
  • Active cancer or psychiatric diseases
  • Excessive alcohol intake ( 2 glasses per day)
  • Untreated or uncontrolled thyroid disorders
  • Cushing disease, polycystic ovaries, neuro-endocrine or drug-induced obesity
  • Untreated gout
  • History of bariatric surgery

AI-Screening

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Trial Site Locations

Total: 1 location

1

American University of Beirut - Medical Center

Beirut, Riad El Solh, Lebanon, 1107 2020

Actively Recruiting

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Research Team

M

Marlene Chakhtoura, MD, MSc

CONTACT

R

Rachelle El Haber, BSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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