Comparison between Silk Sutures and Cyanoacrylate Adhesive in Human Mucosa- A Clinical and Histological Study.
M Suresh Kumar, Sreelakshmi Natta, Gowri Shankar...
https://pubmed.ncbi.nlm.nih.gov/24324311/Actively Recruiting
Led by Recep Tayyip Erdogan University · Updated on 2026-06-09
148
Participants Needed
1
Research Sites
2 weeks
Total Duration
Researchers are evaluating four different flap closure techniques to compare their effects on reducing postoperative problems such as pain, swelling, trismus, and wound healing after impacted mandibular third molar wisdom tooth extraction. The study also aims to assess how these methods impact patient quality of life using the GOHAI questionnaire. This randomized controlled trial focuses on commonly used oral surgery methods to determine the best clinical approach for patient recovery. The techniques being studied include conventional suturing using braided silk sutures, a sutureless method where the wound heals naturally, surgical drain placement to help remove fluids and reduce swelling, and cyanoacrylate tissue adhesive that rapidly closes the wound edges. Each participant will receive one of these four flap closure techniques following their tooth extraction, applied according to a standardized protocol by experienced surgeons. Participants will be monitored with follow-up visits on days 1, 3, 7, and 14 after surgery to measure pain, swelling, trismus, wound healing, and quality of life. The study includes safety monitoring for possible complications such as infection or bleeding, with emergency procedures in place if serious adverse events occur. Participation lasts through the postoperative assessment period, allowing researchers to compare how each technique affects recovery and patient wellbeing.
CONDITIONS
The Effect of Different Flap Closure Techniques on Postoperative Morbidity in Impacted Third Molar Surgery
A
Alperen Kalyoncu, Assistant Professor
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Recep Tayyip Erdogan University
Lead Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single surgical procedure
Participants receive one of four flap closure techniques after impacted mandibular third molar extraction: conventional suturing, sutureless technique, surgical drain placement, or cyanoacrylate tissue adhesive.
1 surgical visit
Duration - 14 days
Participants return for assessments on days 1, 3, 7, and 14 after surgery to measure pain, swelling, trismus, wound healing, and quality of life.
4 follow-up visits
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
4
Have more questions? Get in touch with our team for quick support
M Suresh Kumar, Sreelakshmi Natta, Gowri Shankar...
https://pubmed.ncbi.nlm.nih.gov/24324311/M Madrazo-Jiménez, Á Rodríguez-Caballero, M-Á Serrera-Figallo...
https://pubmed.ncbi.nlm.nih.gov/27475700/Safak Ergül, Gülcan Coskun Akar
https://pubmed.ncbi.nlm.nih.gov/18795563/Saulo Gabriel Moreira Falci, Marco Túllio Becheleni Ávila Guimarães, Nathalia Moore Canarim...
https://pubmed.ncbi.nlm.nih.gov/38267703/M Santmartí-Oliver, S Bazal-Bonelli, L Sánchez-Labrador...
https://pubmed.ncbi.nlm.nih.gov/38907642/Afisu A Oladega, Olutayo James, Wasiu L Adeyemo
https://pubmed.ncbi.nlm.nih.gov/30501926/Archana Sen, Vikas Dhupar, Francis Akkara
https://pubmed.ncbi.nlm.nih.gov/39117914/Aysenur Genc, Sirmahan Cakarer, Basak Keskin Yalcin...
https://pubmed.ncbi.nlm.nih.gov/29675759/Pierluigi Mariani, Dardo Menditti, Diana Russo...
https://pubmed.ncbi.nlm.nih.gov/37177802/Recep Tayyip Erdogan University
Lead Sponsor