Comparing Calcium Hydroxide and Diclofenac Sodium for Healing Periapical Lesions After Root Canal Retreatment Using Fractal Analysis

What this Trial Is About

Researchers are evaluating the effects of two different intracanal medicaments, calcium hydroxide and diclofenac sodium, on the healing of periapical lesions following endodontic retreatment. The study plans to include 54 patients with apical periodontitis after initial root canal treatment. Healing will be monitored by measuring changes in bone regeneration around the tooth using fractal analysis of radiographic images taken at the start and after 12 months. Participants will be randomly assigned to receive either calcium hydroxide or diclofenac sodium as the intracanal medicament. Both medicaments will be prepared in a similar way and placed inside the root canal by a single experienced endodontist under standardized conditions. After one week, the medicaments will be removed, and the root canals will be refilled using established techniques. All procedures use local anesthesia and specialized dental tools to ensure consistency. During the study, patients will undergo clinical and radiographic evaluations at baseline and after one year to assess healing and any symptoms such as pain or swelling. Radiographs will be analyzed by blinded experts to measure the reduction in lesion size. Patients will also be invited for an additional follow-up around four years after treatment to evaluate long-term restoration quality. Safety and treatment effects will be closely monitored throughout the study period.

The Effect of Different Intracanal Medicaments on Periapical Lesion Healing