What is this study trying to find out about physical training and hormone profiles?

This study is investigating how different sex hormone profiles affect muscle growth and adaptation to physical training in women. It also looks at related effects on fat tissue, tendons, and overall physical function. The University of Aarhus is leading this research to better understand these hormone impacts during exercise.

Who may be eligible for this physical training clinical trial?

Women aged 18 to 35 with a body mass index between 19 and 25 may be eligible. Participants should not smoke, exercise more than twice weekly, be pregnant, or take medications that affect study outcomes. Please review eligibility criteria for more details.

Is there any cost to participate in this physical training clinical trial?

Study-related care, including the training program and all trial visits, is provided at no cost. However, personal expenses like travel may vary and might not be covered. Participants can expect free supervised exercise sessions and assessments throughout the study.

Actively Recruiting

Phase Not Applicable

Age: 18Years - 35Years

FEMALE

Healthy Volunteers

ID07115849

Effect of Different Sex Hormone Profiles for the Response to Physical Training

Led by University of Aarhus · Updated on 2026-03-02

Participants Needed

Research Sites

104 weeks

Total Duration

AI-Summary

What this Trial Is About

This research aims to explore how different sex hormone profiles affect muscle mass adaptation to physical training. It also examines secondary effects on fat tissue, tendons, and other body functions related to physical performance. The study involves women with regular menstrual cycles and those using hormonal contraceptives that alter sex hormone levels. Participants are divided into three groups based on their hormone profiles non-hormonal contraception users, intrauterine device IUD users with levonorgestrel, and progestin-only pill users with desogestrel. All will undergo a 4-month physical training program including aerobic and resistance exercises three times a week, with two supervised sessions each week. Measurements occur before, during, and after training. Throughout the study, researchers will assess body composition, diet, physical activity, blood and urine samples, muscle and fat tissue, aerobic capacity, muscle strength, and related questionnaires. The main outcomes focus on changes in muscle mass and fat-free mass after 4 months. Additional measures include muscle fiber types, metabolic rate, oxygen uptake, appetite markers, and lipid profiles. Participants involvement lasts 4 months with ongoing monitoring.

CONDITIONS

Brief Title

Effect of Different Sex Hormone Profiles for the Response to Physical Training

Who Can Participate

Age: 18Years - 35Years

FEMALE

Healthy Volunteers

Eligibility Criteria

You may qualify if you...

Female aged 18 to 35 years
Body mass index (BMI) between 19 and 25
Use of either non-hormonal contraception, IUD with levonorgestrel, or progestin-only pills with desogestrel

You will not qualify if you...

Training more than 2 times per week
Smoking
Pregnancy
Taking medications known to affect study outcome parameters

Research Team

Mette Hansen, PhD

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Effect of Different Sex Hormone Profiles for the Response to Physical Training

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AI-Summary

What this Trial Is About

Brief Title

Who Can Participate

Eligibility Criteria

Research Team

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