Actively Recruiting
The Effect of Different Types of Mouthwash on Extraction Sockets' Healing
Led by University of Jordan · Updated on 2026-05-07
100
Participants Needed
1
Research Sites
68 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to assess the effect of four different types of mouthwash on socket healing after surgical extractions in male or female patients aged 18 years and older who have a unilateral impacted mandibular third molar indicated for extraction. The main questions it aims to answer are: The effect of Bone Bioactive Liquid (BBL) mouthwash, Hyaluronic Acid (HA) mouthwash, the Chlorhexidine digluconate (CHX) mouthwash and Warm Saline Mouth Rinse (WSMR) on socket healing after surgical extractions. The effect of BBL mouthwash, HA mouthwash, the CHX mouthwash and WSMR on patient related factors and their quality of life. Recruited Participants will be randomized into four intervention groups: 1. First group will receive BBL mouthwash. 2. The second group will receive CHX mouthwash. 3. The third group will be prescribed HA mouthwash. 4. The fourth group will receive Warm Saline Mouth Rinse.
CONDITIONS
Official Title
The Effect of Different Types of Mouthwash on Extraction Sockets' Healing
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female patients aged 18 years and older
- Have a unilateral impacted mandibular third molar indicated for extraction with bone removal
- Presence of an adjacent second molar
You will not qualify if you...
- Soft tissue impaction not requiring bone removal
- Any acute oral infection including active Pericoronitis
- Previous radiotherapy in head and neck region, chemotherapy, or systemic long-term corticosteroid treatment
- Use of medications causing gingival hyperplasia such as phenytoin, cyclosporine A, or certain calcium channel blockers
- Use of systemic antibiotics within 3 months prior to baseline
- Uncontrolled diabetes, severe nutritional deficiencies, or endocrine disorders
- Immune deficiency or immune diseases
- Use of intravenous bisphosphonates or oral bisphosphonates for more than 3 years
- Smoking or alcohol use
- Pregnancy or breastfeeding
- Known allergy to any mouthwash ingredients, especially chlorhexidine
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of Jordan hospital
Amman, Jordan, 11941
Actively Recruiting
Research Team
A
Ahmad Hamdan, Ph.D. in Periodontics
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
4
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