Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07465991

The Effect of Digital Cognitive Behavioural Therapy for Insomnia on Physical Activity in Fibromyalgia

Led by University of Oxford · Updated on 2026-03-12

142

Participants Needed

2

Research Sites

104 weeks

Total Duration

On this page

Sponsors

U

University of Oxford

Lead Sponsor

O

Oxford University Hospitals NHS Trust

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if a digital sleep therapy program (digital Cognitive Behavioural Therapy for Insomnia or dCBT-I) works to improve quality of life and movement in adults with fibromyalgia who also have trouble sleeping. The main questions it aims to answer are: * Does digital sleep therapy improve quality of life for people with fibromyalgia? * Does digital sleep therapy improve sleep quality? * Does better sleep help reduce fear of movement and increase physical activity, assessed in a virtual reality (VR) environment? Researchers will compare digital sleep therapy (called 'Sleepio') to standard care with sleep advice materials. Participants will: * Use the Sleepio program at home for 10 weeks (6 sessions, 20 minutes each) * Wear a sleep monitoring device at home in bed for several nights at the start and after 3 months * Wear an activity watch for 1 week to track movement at the start and after 3 months * Complete questionnaires about pain, sleep, mood, and daily activities at the start, 3 months, and 6 months * Visit the study centre twice for assessments that include: * Pain sensitivity testing * A virtual reality game that measures how they move and make decisions * Recording of simple exercises like marching and squats Participation in the study lasts about 6 months.

CONDITIONS

Official Title

The Effect of Digital Cognitive Behavioural Therapy for Insomnia on Physical Activity in Fibromyalgia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Willing and able to provide informed consent for participation in the study
  • Male or female, aged 18 years or above
  • Clinical diagnosis of fibromyalgia or chronic widespread pain
  • Concomitant insomnia, frequent nighttime waking, or early morning waking
  • Self-reported difficulties with concentration or memory
  • Reliable internet access (required to access digital intervention)
Not Eligible

You will not qualify if you...

  • Poor understanding of English
  • Known neurological conditions (other than depression or anxiety) likely to independently affect pain assessment results (e.g., peripheral diabetic neuropathy)
  • Major neuropsychiatric disorder (bipolar disorder, schizophrenia, or psychotic spectrum disorders)
  • Epilepsy
  • Cognitive impairment, dementia, or neurodegenerative disorder
  • Recent surgery (within past 3 months) or planned surgery during study period
  • Current night-time shift work or planned night-time shift work during study period
  • Diagnosed sleep disorders including sleep apnea, restless leg syndrome, circadian rhythm disorder, or parasomnia
  • Taking prescribed sleep medications on more than 2 nights in the past 2 weeks
  • Currently receiving other psychological therapy for insomnia
  • Pregnant or lactating

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Oxford Centre for Integrative Neuroimaging

Oxford, United Kingdom, OX3 9DU

Not Yet Recruiting

2

University of Oxford

Oxford, United Kingdom, OX3 9DU

Actively Recruiting

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Research Team

A

Amanda Wall, BSc MSc

CONTACT

E

Eoin Kelleher, MB BCh DPhil

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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