Actively Recruiting
Effect of Diluent Volume on Colistin Inhalation Therapy
Led by Fu Jen Catholic University · Updated on 2026-02-27
60
Participants Needed
1
Research Sites
124 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study is to investigate the impact of different diluent volumes for the same dosage of colistin in mechanically ventilated respiratory patients receiving colistin inhalation therapy. The study aims to determine whether the diluent volume has an effect on clinical outcomes, including ICU length of stay, total hospitalization duration, duration of respiratory support within 28 days, mortality rates within 28 days and 90 days, as well as analyze the pharmacokinetic profile of colistin in blood and bronchoalveolar lavage fluid. Additionally, the study will evaluate the incidence of nebulizer malfunctions and blockages. The findings of this research will help identify the optimal diluent volume for colistin inhalation therapy in clinical practice.
CONDITIONS
Official Title
Effect of Diluent Volume on Colistin Inhalation Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Admitted to the Intensive Care Unit.
- Age greater than 18 years and using a ventilator due to acute respiratory failure.
- Requires inhalation colistin treatment as determined by the disease.
- Sign the written informed consent form.
You will not qualify if you...
- Renal failure requiring renal dialysis.
- Receiving both inhaled colistin and intravenous colistin treatments.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fu Jen Catholic University Hospital, Fu Jen Catholic University
New Taipei City, Taiwan, 24352
Actively Recruiting
Research Team
K
Ke-Yun Chao, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here