Actively Recruiting
Effect of Early Administration of Albumin 20% Versus Crystalloid
Led by Egymedicalpedia · Updated on 2024-06-06
46
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Sepsis and septic shock are global health problems, leading to a high mortality rate. They are often associated with extremely low blood pressure and multiple organ dysfunctions, which are the main causes of death in critically ill patients. Fluid resuscitation is one of the most critical treatments for patients with sepsis and septic shock. An early administration of an appropriate fluid to patients is considered the most effective way to increase blood pressure, improve tissue perfusion, and save their lives. Crystalloid fluids are a subset of intravenous solutions composed of mineral salts and other small, water-soluble molecules, including normal, isotonic or hypertonic saline, and various buffered solutions.
CONDITIONS
Official Title
Effect of Early Administration of Albumin 20% Versus Crystalloid
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Presence of septic shock defined by clinically possible, probable, or confirmed infection
- Need for vasopressors to maintain mean arterial pressure (MAP) 265 mmHg for at least 1 hour despite adequate volume therapy
- Serum lactate concentration above 2 mmol/l despite adequate volume therapy
- Onset of septic shock less than 24 hours before study inclusion
- Women of childbearing age must have a negative pregnancy test
You will not qualify if you...
- Moribund condition (very near death)
- End of life decisions in place
- Previous participation in this or any other interventional clinical trial
- Known allergy to albumin or any component of the study drug
- Medical conditions where albumin administration may be harmful
- Breastfeeding
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Assuit University hospitals
Asyut, Egypt
Actively Recruiting
Research Team
A
Ahmed Abdelhamed Helal, MSC
CONTACT
N
Noha Yahia Mohamed, Lecturer
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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