Effect of Combined Transcutaneous Electrical Stimulation and Isometric Exercise on Peripheral Hemodynamic Parameters in Patients With Resistant Hypertension

What this Trial Is About

Researchers are evaluating whether combining transcutaneous electrical nerve stimulation (TENS) with isometric exercise (IE) can improve blood pressure in adults aged 50 to 60 who have resistant hypertension. This condition involves blood pressure that remains high despite taking three or more different blood pressure medications at maximum doses. The study aims to understand the effect of this combined approach on various blood pressure and heart function measures compared to conventional physical therapy. Participants will be randomly assigned to one of two groups. The experimental group will receive TENS applied to the upper thoracic spine three times a week for 30 minutes per session, alongside isometric handgrip exercises performed with a dynamometer at 30% of maximum effort, repeated four times per session, also three times weekly, for eight weeks. The control group will follow a conventional physical therapy program including aerobic brisk walking, dynamic resistance weight training, stretching, breathing exercises, and lifestyle advice, also three times per week for eight weeks. Throughout the study, participants will be monitored with heart rate and blood pressure measurements before sessions to ensure safety. Researchers will assess blood pressure parameters including systolic, diastolic, mean arterial pressure, pulse pressure, and heart rate variability over the eight-week period. Secondary measures will include oxygen saturation, quality of life, and functional capacity. The study lasts eight weeks, with treatments and assessments conducted regularly to evaluate the effects of the interventions on resistant hypertension.

Effect of Electrical Stimulation and Exercise on Blood Flow in Patients With Resistant High Blood Pressure