Actively Recruiting
Effect of Electrical Stimulation and Exercise on Blood Flow in Patients With Resistant High Blood Pressure
Led by Mohamed Mohamed Ali Morgan · Updated on 2026-02-03
50
Participants Needed
1
Research Sites
20 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if the combination between transcutaneous electrical nerve stimulation (TENS) and isometric exercise (IE) can improve blood pressure in men and women between 50 to 60 years old suffered from resistant hypertension which is a type of hypertension where blood pressure remains above your target goal despite the use of three or more different classes of antihypertensive medications at their maximum tolerated doses. The main question to answer is: Is there a significant effect on the combined use of TENS and IE on peripheral hemodynamic parameters in patients with resistant hypertension? Total sample will be 50 patients from both sexes I will compare between two groups: Experimental group (15 men, 10 women) will take: medication plus IE and TENS Control group (15 men, 10 women) will take: medication plus Conventional Physical Therapy Program
CONDITIONS
Official Title
Effect of Electrical Stimulation and Exercise on Blood Flow in Patients With Resistant High Blood Pressure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 50 and 60 years, including both men and women
- Diagnosed with hypertension for at least 5 years
- Resistant hypertension defined as systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg despite using three or more antihypertensive medications of different classes including a diuretic, or controlled blood pressure (<140/90 mmHg) while on four or more medications
- Body Mass Index (BMI) between 25 and 34.9 kg/m²
- Increased waist circumference: greater than 102 cm for males or greater than 88 cm for females
You will not qualify if you...
- Secondary hypertension due to identifiable causes such as renal artery stenosis, primary aldosteronism, or pheochromocytoma
- History of major cardiovascular events in the last 6 months including myocardial infarction, stroke, or heart failure exacerbation
- Severe musculoskeletal or neurological disorders that limit safe performance of isometric exercise, such as recent joint replacement, severe osteoarthritis, or stroke with residual motor deficit
- Contraindications to TENS use including implanted electronic devices (pacemakers, defibrillators), uncontrolled arrhythmias, severe skin conditions (open wounds, rashes, burns, eczema), peripheral neuropathy, or sensory loss
- Known cognitive impairment or psychiatric conditions that impair ability to follow instructions or provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Out Clinics of Port Said Hospitals
Port Said, Port Said Governorate, Egypt, 42515
Actively Recruiting
Research Team
M
Mohamed Mohamed Morgan, Bachelor of Physical Therapy
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here