Actively Recruiting
Effect of EMDR for Reduction of Pain Interference in Children With Sickle Cell Disease
Led by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Updated on 2025-06-03
40
Participants Needed
1
Research Sites
144 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Children with sickle cell disease may experience frequent painful episodes. This, together with the traumatic experiences during a hospitalization, can lead to the development of posttraumatic stress reactions. As the stress can trigger painful episodes (pain crisis) in children with sickle cell disease, the investigators think that treating these stress symptoms can reduce the pain-related problems in their lives. Eye Movement Desensitization and Reprocessing (EMDR) is proven to be an effective trauma treatment for posttraumatic stress disorder. Research studies show that EMDR can reduce pain in adults. The investigators want to study now if EMDR effective is in reducing pain-related problems in children with sickle cell disease.
CONDITIONS
Official Title
Effect of EMDR for Reduction of Pain Interference in Children With Sickle Cell Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Medical diagnosis of sickle cell disease
- Age between 6 and 18 years old
- Elevated pain interference scores above the clinical cut-off T-score of 49 on PROMIS Pain Interference (parent-proxy version for children 6-7 years and self-report for children 8 years and older)
- Sufficient knowledge of Dutch or English to complete assessments
You will not qualify if you...
- Undergone successful stem cell transplantation
- Pregnant adolescents
- Current unsafety likely to interfere with therapy, such as ongoing domestic violence
- Major acute medical or psychiatric condition interfering with participation, including psychosis, substance dependence, severe self-harm, or high suicide risk requiring immediate treatment
- Receiving psychological trauma treatment by another therapist
- Estimated IQ below 80 based on medical or educational records
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Amsterdam UMC
Amsterdam, Netherlands
Actively Recruiting
Research Team
M
Mariana Nery, MD
CONTACT
L
Linde Scholten
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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