Actively Recruiting
Effect of Er,Cr:YSGG Sub-Ablative Laser Irradiation on Fissure Caries Prevention in Permanent Molars
Led by Alexandria University · Updated on 2025-02-14
60
Participants Needed
1
Research Sites
82 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Background: Subjecting human dental enamel to sub-ablative laser has been suggested as a novel way of caries prevention. However, further studies are needed to establish its use as a routine clinical procedure for caries prevention. The aim of this study: This study aims to evaluate the effect of Er,Cr:YSGG subablative laser irradiation on caries resistance of occlusal fissures of permanent molars. Materials and methods: In-vivo study, a split mouth randomized controlled trial with sixty patients having two fully erupted bilateral first permanent molars (ICDAS-II score 0,1 or 2). The pits and fissures will be subjected to sub-ablative power of Er,Cr:YSGG Laser (Group 1, n=90) and will be compared with fluoride varnish application on the first permanent molars in the same arch(Group 2,n=90). DIAGNOdentTM readings and changes in ICDAS-II score will be assessed at base line and at 3,6,9 and 12 months follow-up.
CONDITIONS
Official Title
Effect of Er,Cr:YSGG Sub-Ablative Laser Irradiation on Fissure Caries Prevention in Permanent Molars
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children aged 6 to 12 years old
- Positive or definitely positive behavior on Frankl behavior rating scale
- At least two fully erupted bilateral first permanent molars with untreated, non-cavitated occlusal surfaces having ICDAS-II scores 0, 1, or 2
- Initial DIAGNOdent score not exceeding 25, indicating only enamel involvement
- Parents willing to comply with study procedures and provide informed consent
You will not qualify if you...
- Known medical history of systemic diseases
- First permanent molars with hypoplastic or hypocalcified enamel
- Use of medications affecting oral flora or saliva flow
- In-office fluoride treatment within 3 months prior to enrollment
- Evidence of poor oral hygiene assessed by Silness and Löe plaque index
AI-Screening
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Trial Site Locations
Total: 1 location
1
Alexandria University
Alexandria, Egypt
Actively Recruiting
Research Team
H
Hussein Ezz Eldin
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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