Opioid-free Analgesia for Posterior Spinal Fusion Surgery Using Erector Spinae Plane (ESP) Blocks in a Multimodal Anesthetic Regimen.
Ki Jinn Chin, Stephen Lewis
https://pubmed.ncbi.nlm.nih.gov/30180150Actively Recruiting
Phase 3
Age: 10Years - 18Years
All Genders
ID07561827
The Effect of Erector Spinae Plane Block (ESPB) on Pediatric Pain Management Following Posterior Spinal Fusion Surgery
Led by University of California, San Francisco · Updated on 2026-05-01
42
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating how well an erector spinae plane block (ESPB) works for managing pain in children aged 10 to 18 with Adolescent Idiopathic Scoliosis or Neuromuscular Scoliosis who are having Posterior Spinal Fusion surgery. The study aims to see if adding ESPB reduces pain and the need for pain medication after surgery. ESPB involves injecting a local anesthetic called ropivacaine into back muscles to block pain signals. Participants will be randomly assigned to one of two groups: one group will receive the ESPB with ropivacaine along with the usual postoperative pain treatment, while the other group will receive only the standard postoperative pain treatment without the ESPB. This is a phase 3 trial with single masking to compare these approaches. The study treatment occurs during surgery and follows with standard pain management. During the first 72 hours after surgery, researchers will track the amount of oral morphine and benzodiazepines used, as well as pain scores within the first 24 hours. They will also measure how quickly participants are cleared to start physical therapy after surgery. The study will monitor these outcomes carefully to understand the impact of ESPB on pain control and recovery. The trial is sponsored by the University of California, San Francisco and runs until early 2027.
CONDITIONS
Brief Title
The Effect of Erector Spinae Plane Block (ESPB) on Pediatric Pain Management Following Posterior Spinal Fusion (PSF) Surgery
Who Can Participate
Age: 10Years - 18Years
All Genders
Eligibility Criteria
You may qualify if you...
- Diagnosis of Adolescent Idiopathic Scoliosis (AIS) or neuromuscular scoliosis
- Scheduled to undergo Posterior Spinal Fusion (PSF) Surgery
- Age between 10 and 18 years
You will not qualify if you...
- Patients with scoliosis types other than AIS or neuromuscular scoliosis
- Undergoing spinal deformity correction surgery other than Posterior Spinal Fusion Surgery
- Allergy or contraindication to erector spinae plane block (ESPB) with Ropivacaine
- Taking opioid medications before surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Surgery and Immediate Post-operative Care
Duration - Hospital stay during surgery and immediate recovery
Participants undergo Posterior Spinal Fusion surgery and receive either an erector spinae plane block with Ropivacaine along with standard postoperative pain management or standard postoperative pain management alone.
1 hospital stay visit (in-person)
Post-operative Follow-up
Duration - Up to 72 hours after surgery for pain assessment; physical therapy until clearance
Participants are monitored for pain management effectiveness and recovery, including evaluation of opioid use, pain scores, and physical therapy clearance.
Multiple visits for up to 3 days post-surgery and ongoing physical therapy visits until clearance
Trial Site Locations
Total: 1 location
1
University of California San Francisco
San Francisco, California, United States, 94158
Actively Recruiting
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Research Team
T
Tripta Rughwani
S
Stephanie Chu
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Published Research Related To This Trial
The Role of Liposomal Bupivacaine in Multimodal Pain Management Following Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis: Faster and Farther With Less Opioids.
Stuart Changoor, Alec Giakas, Karen Sacks...
https://pubmed.ncbi.nlm.nih.gov/37159268Bilateral bi-level erector spinae plane blocks in scoliosis surgery: a retrospective comparative study.
Selcan Akesen, Saltuk Buğra Güler, Burak Akesen
https://pubmed.ncbi.nlm.nih.gov/36300557Moving toward patients being pain- and spasm-free after pediatric scoliosis surgery by using bilateral surgically-placed erector spinae plane catheters.
Ban C H Tsui, Mohammad Esfahanian, Carole Lin...
https://pubmed.ncbi.nlm.nih.gov/31776896Bilateral erector spinae plane block for scoliosis surgery: Case series.
S M Diwan, E Yamak Altinpulluk, K Khurjekar...
https://pubmed.ncbi.nlm.nih.gov/32057483Low thoracic erector spinae plane block for perioperative analgesia in lumbosacral spine surgery: a case series.
Josh P Melvin, Rudolph J Schrot, George M Chu...
https://pubmed.ncbi.nlm.nih.gov/29704223Bilateral lumbar ultrasound-guided erector spinae plane block versus local anesthetic infiltration for perioperative analgesia in lumbar spine surgery: a randomized controlled trial.
Alessandro Vergari, Luciano Frassanito, Mariangela DI Muro...
https://pubmed.ncbi.nlm.nih.gov/35191639The effect of ultrasound-guided erector spinae plane block on postsurgical pain: a meta-analysis of randomized controlled trials.
Mark C Kendall, Lucas Alves, Lauren L Traill...
https://pubmed.ncbi.nlm.nih.gov/32357842The Erector Spinae Plane Block: A Novel Analgesic Technique in Thoracic Neuropathic Pain.
Mauricio Forero, Sanjib D Adhikary, Hector Lopez...
https://pubmed.ncbi.nlm.nih.gov/27501016