Actively Recruiting

Age: 18Years +
All Genders
NCT05380791

Effect of Esophageal Contractile Reserve on Changes in Esophageal Motility and Symptoms After ARS in Patients With GERD

Led by Shandong University · Updated on 2022-05-19

70

Participants Needed

1

Research Sites

214 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

rapid swallow (MRS) can assess the contractile reserve capacity of the oesophageal body and identify and diagnose oesophageal motility disorders, but the impact of preoperative oesophageal reserve capacity on postoperative symptoms and motility in patients with GERD remains unclear. The aim of this study was to assess the effect of pre-operative oesophageal reserve capacity on post-reflux symptoms and motility in patients with GERD by using a high-resolution oesophageal manometry-based provocation test, MRS, to track pre-operative ineffective oesophageal motility (IEM).

CONDITIONS

Official Title

Effect of Esophageal Contractile Reserve on Changes in Esophageal Motility and Symptoms After ARS in Patients With GERD

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 18 years old
  • Patients to be treated surgically for gastroesophageal reflux disease
  • Ineffective esophageal motility diagnosed by high resolution esophageal manometry according to Chicago Classification version 4.0
  • Obtaining Informed Consent
Not Eligible

You will not qualify if you...

  • Previous other upper gastrointestinal surgery
  • Pregnant women and other people with contraindications to surgery and tests
  • Other specifically defined esophageal motility disorders, such as nutcracker esophagus

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department of Gastroenterology, Qilu Hospital, Shandong University

Jinan, Shandong, China, 250012

Actively Recruiting

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Research Team

F

FeiXue Chen, MD

CONTACT

Y

Yanqing Li, phD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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