Actively Recruiting
The Effect of Eyeliner on Tear Composition, Tear Secretion and Tear Film Stability.
Led by Zhongnan Hospital · Updated on 2025-09-29
80
Participants Needed
1
Research Sites
201 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Eyeliner is one of the most common eye cosmetics. The main ingredients are titanium oxide, pigment, grease and preservative. The user will apply the eyeliner to the eyelid and eyelash. With the blinking again and again, the components of the eyeliner may enter the tear film and continue to act on the eye surface. Therefore, the investigators suspect that the use of eyeliner may be an important factor leading to dry eye disease. In order to explore the relationship between the use of eyeliner and dry eye disease, the investigators plan to collect eye surface characteristic data of the two groups of people who use eyeliner and who do not use it.Then use Raman analysis to explore whether the use of eyeliner will lead to changes in tear composition.The investigators intend to analyze the difference of tear composition between the two groups to understand the relationship between the change of tear composition and tear film stability.So that the investigators can identify the risk factors of dry eye disease, and provide basis for prevention and early treatment.
CONDITIONS
Official Title
The Effect of Eyeliner on Tear Composition, Tear Secretion and Tear Film Stability.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- People aged 20 to 35 who use eyeliner or do not use eyeliner.
- People who use eyeliner have used it for at least 1 year and at a frequency of 3 or more times per week.
You will not qualify if you...
- Other serious systemic diseases.
- Systemic diseases related to the eye surface like rheumatoid arthritis, systemic lupus erythematosus, Sjogren's syndrome, other immune system diseases, or other eye diseases.
- History of eye surgery or trauma.
- Lactating women or pregnant women.
- Use of electronic products for more than 4 hours daily.
- Patients with circadian rhythm disorder.
- History of radiation exposure.
- Non-permanent residents of Wuhan.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Zhongnan Hospital of Wuhan University
Wuhan, Hubei, China, 430071
Actively Recruiting
Research Team
M
Min Ke
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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