Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT06835322

Effect of Finerenone in Patients With Non-diabetic Glomerulonephritis

Led by Alexandria University · Updated on 2025-03-26

100

Participants Needed

1

Research Sites

28 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to assess the effect of finerenone on proteinuria and GFR progression in patients with non-diabetic glomerulonephritis.

CONDITIONS

Official Title

Effect of Finerenone in Patients With Non-diabetic Glomerulonephritis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Biopsy-proven glomerulonephritis patients on maximum tolerated doses of ACE inhibitors or ARBs plus immunosuppression if needed for at least 4 weeks
  • Urinary protein excretion greater than 500 mg/g
  • Adults aged 18 years and older
  • Estimated glomerular filtration rate (eGFR) of 25 mL/min/1.73 m2 or higher
  • Baseline serum potassium level below 5 mEq/L
Not Eligible

You will not qualify if you...

  • Diabetes mellitus (type 1 or 2)
  • Other non-glomerular kidney diseases
  • Heart failure
  • Pregnancy or breastfeeding
  • Use of hyperkalemia treatments within 4 weeks before study
  • Uncontrolled high blood pressure (greater than 160/100)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Faculty of Medicine, Aexandria University

Alexandria, Egypt, 21526

Actively Recruiting

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Research Team

M

Mohamed Mamdouh Elsayed, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Effect of Finerenone in Patients With Non-diabetic Glomerulonephritis | DecenTrialz