Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
All Genders
Healthy Volunteers
NCT06933290

Effect of Flavored, Carbonated Drinks on Salivary Flow, Salivary Composition, and Taste Perceptions

Led by PepsiCo Global R&D · Updated on 2025-04-18

13

Participants Needed

1

Research Sites

13 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To determine the effect of flavored, carbonated drinks on salivary flow rate, saliva composition, and taste perceptions compared with control drinks (water, carbonated water, non-carbonated)

CONDITIONS

Official Title

Effect of Flavored, Carbonated Drinks on Salivary Flow, Salivary Composition, and Taste Perceptions

Who Can Participate

Age: 18Years - 45Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Subject is male or female
  • If female, subject is not pregnant or nursing (based on self-report)
  • Subject is 18-45 years of age, inclusive
  • Subject is a regular consumer of carbonated drinks (questionnaire)
  • Subject is willing to avoid alcohol consumption 24 hours prior to visits
  • Subject is willing to fast (no food or gum) for 2 hours prior to study sessions
  • Able to speak, write, and read English
  • Provision of written consent to participate
Not Eligible

You will not qualify if you...

  • Subject smokes, vapes, or uses any nicotine/tobacco products (or has quit for less than 6 months)
  • Subject currently has or recently had an illness (cold, flu, COVID) within the past month
  • Subject has a condition affecting the oral cavity such as Xerostomia (dry mouth), Sores/lesions, Untreated dental caries, Major dental implants/appliances (including dentures)
  • Subject has a reduced sense of taste (dysgeusia) or smell (parosmia)
  • Subject has a health condition that would interfere with the study as indicated on the general health questionnaire (GHQ) (including cardiovascular, renal, or metabolic diseases)
  • Subject has participated in a clinical trial within the past 30 days
  • Subject has participated in any PepsiCo trial within past 6 months
  • Subject has a condition or is taking medication that the investigator believes would interfere with his/her ability to provide informed consent, comply with the study protocol, which might confound the interpretation of the study results, or put the person at undue risk
  • Subject is employed by, or has a parent, guardian, or other immediate family member employed by a company that manufactures any products that compete with any PepsiCo product. If subject is unsure if a company would be considered a competitor to PepsiCo, they will be asked to please let the study investigator know the name of the other company and the nature of their relationship to that company before they sign the informed consent.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Gatorade Sports Science Institute

Valhalla, New York, United States, 10595

Actively Recruiting

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Research Team

L

Lindsay Baker, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

6

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