Actively Recruiting

Phase Not Applicable
Age: 11Years - 16Years
All Genders
Healthy Volunteers
NCT06668194

Effect of Force Magnitude on Canine Retraction and Gingival Crevicular Fluid Proteome

Led by UConn Health · Updated on 2024-11-26

40

Participants Needed

1

Research Sites

176 weeks

Total Duration

On this page

Sponsors

U

UConn Health

Lead Sponsor

C

Charles Burstone Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study aims to examine the effect of force levels in orthodontic treatment during canine retraction. Force levels refer to the pressure applied by the orthodontic devices to move teeth. Data collection will include gingival fluid, dental molds from a digital scanner, and x-rays of the upper canine region on both sides of the mouth during treatment. The null hypothesis to be tested is that there is no significant difference in the rate of canine movement between the light force and the heavy force levels.

CONDITIONS

Official Title

Effect of Force Magnitude on Canine Retraction and Gingival Crevicular Fluid Proteome

Who Can Participate

Age: 11Years - 16Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy patient, non-smoker
  • Age: 11 - 16 years of age, inclusive.
  • A full complement of dentition (central incisor to 1st molar) in the four quadrants, except second molars
  • Patients requiring at least upper bilaterally maxillary 1st premolar extraction as a treatment plan (Class I bimaxillary protrusion/ crowding or Class II maxillary dentoalveolar protrusion/ crowding)
  • At least 5 mm of space left between canine and 2nd premolar to be closed at the time of canine retraction
  • At least six months after the extraction of first premolars and in a 0.019 x 0.025-inch stainless steel archwire in the maxilla
  • The ability to read and understand English and to provide informed consent
Not Eligible

You will not qualify if you...

  • Patients under 11 years of age and over the age of 16.
  • Non-extraction treatment plan
  • Extraction of maxillary tooth other than first premolars bilaterally.
  • Evidence of poor oral hygiene
  • Evidence of previous root resorption
  • Missing or impacted tooth in any of the quadrant except 3rd molars.
  • Medical issues that affect tooth movement
  • Inability to provide oral and written consent to participate.
  • Patient on medications that may alter bone metabolisms like bisphosphonates, oral contraceptives, or PTH (parathyroid hormone)
  • Chronic illness or syndromic patients.
  • Pregnant women, prisoners, and decisional impaired

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Trial Site Locations

Total: 1 location

1

Department of Orthodontics

Farmington, Connecticut, United States, 06032

Actively Recruiting

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Research Team

F

Flavio Uribe, DDS, MDentSc

CONTACT

G

Georgiana Defilio

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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