Actively Recruiting

Phase Not Applicable
Age: 40Years - 80Years
All Genders
NCT06386614

Effect of Frontal Transcranial Direct Current Stimulation on BDNF in Stroke Patients With Cognitive Impairment

Led by The Second Affiliated Hospital of Dalian Medical University · Updated on 2024-05-21

40

Participants Needed

2

Research Sites

73 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of the clinical trial is to find a treatment for stroke patients with cognitive impairment, and the main questions it aims to answer are: * \[Search for effective treatments of cognitive impairment after stroke\] * \[explore the relationship between BDNF level and cognitive function\] Participants will receive conventional treatment, tDCS treatment, .And then compare cognitive function and BDNF level

CONDITIONS

Official Title

Effect of Frontal Transcranial Direct Current Stimulation on BDNF in Stroke Patients With Cognitive Impairment

Who Can Participate

Age: 40Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Stroke confirmed by CT or MRI imaging
  • Ischemic stroke must meet Chinese Guidelines for Acute Ischemic Stroke 2018
  • Cerebral hemorrhage must meet Chinese Guidelines for Cerebral Hemorrhage 2019
  • Presence of cognitive dysfunction symptoms assessed by rehabilitation physicians
  • MoCA score 26 points or less
  • MMSE score depending on education level: illiteracy 17 or less, primary school 20 or less, secondary school 22 or less, college 23 or less
  • Age between 40 and 80 years old
  • No obvious aphasia; able to cooperate with evaluation and treatment
  • Patient or family member has signed informed consent
Not Eligible

You will not qualify if you...

  • Severe diseases like malignant arrhythmia, acute myocardial infarction, or acute heart failure preventing rehabilitation
  • Untreated intracranial aneurysms, severe epilepsy, or intracranial metals preventing tDCS treatment
  • Cognitive impairment not related to post-stroke cognitive impairment (e.g., from previous stroke or other organ disorders)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Department of Rehabilitation Medicine, the Second Hospital of Dalian Medical University

Dalian, Liaoning, China, 116021

Completed

2

Lily

Dalian, Liaoning, China, 116021

Actively Recruiting

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Research Team

Y

Yang Tu

CONTACT

R

Ren

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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