Actively Recruiting
Effect of Functional Power Training on Calf Muscle Size and Strength in Children With Spastic Paresis
Led by Amsterdam UMC, location VUmc · Updated on 2025-01-08
23
Participants Needed
1
Research Sites
171 weeks
Total Duration
On this page
Sponsors
A
Amsterdam UMC, location VUmc
Lead Sponsor
R
Reade Rheumatology Research Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
Spastic paresis (SP) is a common motor condition in children, often caused by cerebral palsy, leading to altered muscle development such as reduced muscle strength and length, especially in the calf muscles. These changes affect their ability to walk and run, limiting participation in daily activities. This research aims to evaluate the effect of functional power training (MegaPower) on the muscle morphology of the medial gastrocnemius muscle in children with SP, focusing on muscle volume and length changes using 3D ultrasonography. The study uses a double-baseline design with three measurement times to compare the training period with usual care. Participants will undergo functional power training consisting of weighted running and walking exercises performed at high speed, three times a week for 12 weeks. This training aims to improve calf muscle strength and performance. Measurements of muscle volume, muscle belly length, tendon length, and fascicle length will be taken 12 weeks before training, at the start of training, and at the end of training to assess changes over time. Children will be assessed through 3D ultrasonography at three different times to monitor muscle morphology changes. Researchers will measure muscle volume and lengths of muscle belly, tendon, and fascicles before and after the training period. The study will also track muscle strength and performance during functional walking tests. Participation in the study lasts at least 24 weeks, including a 12-week baseline period and a 12-week training period, allowing comparison between usual care and the training effects.
CONDITIONS
Official Title
Effect of Functional Power Training on Calf Muscle Length and Strength in Children With Spastic Paresis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children classified as Gross Motor Function Classification System levels I to III
- Able to lie on their stomach for at least one minute
- Able to follow instructions
You will not qualify if you...
- Received casting within six months prior to study
- Received botulinum toxin type-A injections within six months prior to study
- Received orthopedic surgery within six months prior to study
AI-Screening
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Trial Site Locations
Total: 1 location
1
Reade
Amsterdam, Netherlands, 1056 AB
Actively Recruiting
Research Team
M
Marjolein M van der Krogt, Dr.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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