Actively Recruiting

Age: 4Years - 18Years
All Genders
ID05649930

Effect of Functional Power Training on Calf Muscle Size and Strength in Children With Spastic Paresis

Led by Amsterdam UMC, location VUmc · Updated on 2025-01-08

23

Participants Needed

1

Research Sites

171 weeks

Total Duration

On this page

Sponsors

A

Amsterdam UMC, location VUmc

Lead Sponsor

R

Reade Rheumatology Research Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

Spastic paresis (SP) is a common motor condition in children, often caused by cerebral palsy, leading to altered muscle development such as reduced muscle strength and length, especially in the calf muscles. These changes affect their ability to walk and run, limiting participation in daily activities. This research aims to evaluate the effect of functional power training (MegaPower) on the muscle morphology of the medial gastrocnemius muscle in children with SP, focusing on muscle volume and length changes using 3D ultrasonography. The study uses a double-baseline design with three measurement times to compare the training period with usual care. Participants will undergo functional power training consisting of weighted running and walking exercises performed at high speed, three times a week for 12 weeks. This training aims to improve calf muscle strength and performance. Measurements of muscle volume, muscle belly length, tendon length, and fascicle length will be taken 12 weeks before training, at the start of training, and at the end of training to assess changes over time. Children will be assessed through 3D ultrasonography at three different times to monitor muscle morphology changes. Researchers will measure muscle volume and lengths of muscle belly, tendon, and fascicles before and after the training period. The study will also track muscle strength and performance during functional walking tests. Participation in the study lasts at least 24 weeks, including a 12-week baseline period and a 12-week training period, allowing comparison between usual care and the training effects.

CONDITIONS

Official Title

Effect of Functional Power Training on Calf Muscle Length and Strength in Children With Spastic Paresis

Who Can Participate

Age: 4Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children classified as Gross Motor Function Classification System levels I to III
  • Able to lie on their stomach for at least one minute
  • Able to follow instructions
Not Eligible

You will not qualify if you...

  • Received casting within six months prior to study
  • Received botulinum toxin type-A injections within six months prior to study
  • Received orthopedic surgery within six months prior to study

AI-Screening

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Trial Site Locations

Total: 1 location

1

Reade

Amsterdam, Netherlands, 1056 AB

Actively Recruiting

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Research Team

M

Marjolein M van der Krogt, Dr.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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