Actively Recruiting
Effect of Gastrectomy on Gut Microbiome and Cognitive Function
Led by Jiangjiang Bi · Updated on 2024-04-11
45
Participants Needed
1
Research Sites
123 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Perioperative neurocognitive disorders is a common postoperative complication in elderly surgical patients. The role of gut microbiota in cognitive function has been concerned in recent years. Studies suggests that gastrointestinal surgery may affect the gut microbiota, and the effect varies between surgical procedures. In this study, the investigators will compare the differences of gut microbiota between total gastrectomy and double-tract reconstruction, to investigate the effect of gastric acid on the gut microbiota colonizing, and the effect of different surgical procedures on the postoperative cognitive function of proximal gastric cancer patients.
CONDITIONS
Official Title
Effect of Gastrectomy on Gut Microbiome and Cognitive Function
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis of proximal gastric cancer and scheduled for gastrectomy
- American Society of Anesthesiologists (ASA) classification I-III
- Aged 40 to 80 years
- Perioperative consciousness
You will not qualify if you...
- Central nervous system or psychological disorders
- Chronic use of sedatives or antidepressants within the last year
- Parkinson's disease
- Severe immunosuppression
- Severe hearing or vision impairment
- Drug dependence or alcoholism
- Inability to communicate with a physician
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Tongji Hospital
Wuhan, Hubei, China, 430030
Actively Recruiting
Research Team
J
Jiangjiang Bi, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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