Actively Recruiting
Effect of Genetic Polymorphism on Capecitabine-Induced Toxicity in Egyptian Cancer Patients
Led by Ain Shams University · Updated on 2025-01-09
80
Participants Needed
1
Research Sites
69 weeks
Total Duration
On this page
Sponsors
A
Ain Shams University
Lead Sponsor
M
Menoufia University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this observational study is to study the effect of a single nucleotide polymorphism in the CES1 gene (rs2244613) on capecitabine-induced toxicity in Egyptian cancer patients. This study will help in understanding the interindividual variability in the CES1 gene and the effect of a single nucleotide polymorphism in this gene (rs2244613) on capecitabine-induced toxicity in participants already taking capecitabine-based chemotherapy as part of their regular medical care.
CONDITIONS
Official Title
Effect of Genetic Polymorphism on Capecitabine-Induced Toxicity in Egyptian Cancer Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with breast or colorectal cancer receiving capecitabine-based chemotherapy
- Age over 18 years
- ECOG performance status 0-2
You will not qualify if you...
- Patients treated with irinotecan
- Lack of physical integrity of the upper gastrointestinal tract
- Patients with malabsorption syndrome
- Patients unable to take oral medication
- Patients with poor performance status
- Patients with chronic diarrhea due to ulcerative colitis or Crohn's disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Clinical Oncology, Faculty of Medicine, Menoufia University
Shibīn al Kawm, Menoufia, Egypt, 32511
Actively Recruiting
Research Team
R
Raghad Nassar, Teaching Assistant
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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