Actively Recruiting
The Effect of Graded Forced Expiration on Intraocular Pressure Using the Airofit Device
Led by Uşak University · Updated on 2025-12-22
60
Participants Needed
1
Research Sites
2 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to understand how intraocular pressure (IOP), an important factor linked to glaucoma risk, changes during controlled respiratory stress using the Airofit device. The study focuses on measuring IOP variations across six different levels of forced expiration to provide detailed information about the relationship between respiratory effort and IOP. This will help establish a new standardized method for studying IOP changes during breathing exercises. Participants will use the Airofit respiratory muscle trainer to perform forced expiration maneuvers at six increasing resistance levels, from Level 1 (lowest) to Level 6 (highest). Each level involves a 5-minute exercise phase of forced expiration, immediately followed by an IOP measurement within 5 seconds. This protocol will be done sequentially for all six levels during a single visit. During the study visit, participants will have baseline IOP measured before starting the exercises. After each 5-minute forced expiration session at each resistance level, IOP will be measured promptly. Researchers will collect a total of seven IOP readings per participant, including the baseline and after each level. The study will include about 60 adults who can follow instructions and have certain eye measurements within set ranges. This single-visit study will provide detailed data on how IOP responds to graded respiratory effort.
CONDITIONS
Brief Title
The Effect of Graded Forced Expiration on Intraocular Pressure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 years or older
- Willing and able to provide informed consent
- Have a best-corrected visual acuity of 6/12 or better
- Able to understand and follow instructions for using the Airofit device
- Have an optic nerve cup/disc ratio not exceeding 0.5, and have a cup-to-disc difference between both eyes not exceeding 0.2
- Have not taken any anticholinergic medication, systemic beta-blockers, or corticosteroids within the last 3 months that could affect intraocular pressure levels
You will not qualify if you...
- History of intraocular surgery
- History of uveitis
- Spherical refractive error exceeding 3 diopters
- History of regular topical treatment other than artificial tears
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single visit
Participants undergo a single session where intraocular pressure measurements are taken before and after performing graded forced expiration exercises using the Airofit device.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
University of Usak
Uşak, Turkey (Türkiye), 64200
Actively Recruiting
Research Team
A
Ata Baytaroglu, Asst. Prof.
S
Serife N Ciftci, Asst. Prof.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SCREENING
Number of Arms
1
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here