Actively Recruiting
Effect of HIIT on Post-Stroke Fatigue
Led by The Hong Kong Polytechnic University · Updated on 2025-12-09
60
Participants Needed
1
Research Sites
102 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to investigate the effect of high-intensity interval training (HIIT) on fatigue severity among individuals with chronic stroke. Participants will be randomly assigned to the HIIT group, the moderate-intensity continuous training (MICT) group, or the stretching group (active control). Each group will participate in supervised exercise sessions three times per week over a 12-week period, totaling 36 sessions. Outcome assessments will be conducted at baseline, mid-intervention (week 6), post-intervention (week 12), and follow-up (week 20). The primary outcome will be fatigue severity. Secondary outcomes will include inflammatory biomarkers and additional health-related indicators.
CONDITIONS
Official Title
Effect of HIIT on Post-Stroke Fatigue
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age of 40-80 years
- History of ischemic stroke causing one-sided limb impairment 6-60 months before joining
- Stable medical condition
- Subjective fatigue lasting at least 2 weeks during the past month
- Ability to communicate and no significant cognitive problems
- Ability to walk 10 meters with or without a walking aid
You will not qualify if you...
- Fatigue Severity Scale score less than 4
- Other neurological conditions
- Musculoskeletal issues preventing safe exercise
- Significant cardiovascular, lung, or metabolic diseases
- Symptoms of cardiovascular, lung, or metabolic diseases in past 3 months
- Severe lower limb spasticity (Ashworth Scale score 3 or higher)
- Botulinum toxin use in affected leg within past 6 months
- Current or past use of drugs to treat post-stroke fatigue
- Participation in other stroke rehabilitation trials
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Hong Kong Polytechnic University
Kowloon, Hong Kong
Actively Recruiting
Research Team
M
Mei Zhen Prof. Huang
CONTACT
F
Fong Sze Chung
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here