Actively Recruiting

Phase 1
Phase 2
Age: 18Years - 40Years
FEMALE
Healthy Volunteers
NCT06219018

Effect of Honey For CIN II

Led by Zuyderland Medisch Centrum · Updated on 2025-06-18

60

Participants Needed

2

Research Sites

152 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The following hypothesis is tested: Medical grade honey in CIN II causes a higher clearance of the hr-HPV virus and an increase in the normalization of CIN II lesions compared to expectant management.

CONDITIONS

Official Title

Effect of Honey For CIN II

Who Can Participate

Age: 18Years - 40Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Women aged 18 to 40 years
  • Primary CIN II confirmed by biopsy during colposcopic examination
  • Sufficient mastery of the Dutch language
Not Eligible

You will not qualify if you...

  • Presence of abnormal columnar epithelial cells (AIS)
  • Negative cytology for high risk HPV
  • Use of immunosuppressants or autoimmune diseases such as HIV or CVID
  • History of cervical cancer or previous treatment for CIN (LLETZ or imiquimod)
  • Pregnancy or intention to become pregnant during the study period
  • Legal incompetence
  • Known allergies to honey

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Zuyderland MC

Heerlen, Limburg, Netherlands, 6149 PC

Actively Recruiting

2

Maastricht University Medical Centre+

Maastricht, Limburg, Netherlands, 6229 HX

Not Yet Recruiting

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Research Team

J

Jordy Mongula, dr.

CONTACT

J

Jasmijn Prop, Drs.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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