The Effect Of Using Hypotension Prediction Index To Reduce Intraoperative Hypotension In Caesarean Sections: A Randomised Controlled Trial

What this Trial Is About

Researchers are evaluating the use of the Hypotension Prediction Index (HPI) device to reduce the duration and severity of low blood pressure (hypotension) during lower segment caesarean sections performed under spinal anaesthesia. This study focuses on whether predicting hypotension before it occurs can improve outcomes for both mother and baby, compared to standard blood pressure monitoring. The trial is a randomized controlled study conducted by the National University of Malaysia. The study compares two groups: one using the HPI device with the Acumen IQ cuff, allowing the anaesthetist to view and respond to haemodynamic parameters, and a second group where the anaesthetist is blinded to HPI data and uses standard non-invasive blood pressure monitoring. The HPI device is non-invasive and predicts hypotension earlier than traditional methods, potentially enabling proactive treatment. The study assesses outcomes during the caesarean section surgery. Participants will be monitored from the time spinal anaesthesia is administered until the surgery is completed. Researchers will measure the time-weighted average of mean arterial pressure below 65 mmHg as the primary outcome. Secondary measures include maternal outcomes like nausea, vomiting, blood loss, hospital stay length, satisfaction, and surgical site infection, as well as neonatal outcomes like Apgar scores, umbilical cord pH, and neonatal hospital stay. The study includes assessments up to two weeks after surgery to gather comprehensive safety and effectiveness data.

The Effect of HPI to Reduce Intraoperative Hypotension in Caesarean Sections