Actively Recruiting
Effect of Human Urinary Kallidinogenase on Inflammatory Factors in Acute Ischemic Stroke (KIF-AIS)
Led by First Affiliated Hospital of Harbin Medical University · Updated on 2024-11-20
200
Participants Needed
1
Research Sites
100 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to explore the changes in the expression levels of inflammatory factors before and after the early treatment of Human Urinary Kallidinogen (HUK) in the acute ischemic stroke. It will also learn about the correlation between inflammatory factors and AIS prognosis, in order to clarify the efficacy and safety of Urinary Kallidinogen in the acute phase of AIS.
CONDITIONS
Official Title
Effect of Human Urinary Kallidinogenase on Inflammatory Factors in Acute Ischemic Stroke (KIF-AIS)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with acute ischemic stroke according to 2018 Chinese guidelines
- First clinical onset or previous cerebral infarction without severe lasting effects (Premorbid mRS ≤2)
- Age 18 years or older, any gender
- Baseline NIH Stroke Scale score between 3 and 25
- Provided written informed consent by patient or legal representative
You will not qualify if you...
- Cerebral hemorrhage or other acute hemorrhagic diseases
- Allergy or intolerance to injectable Human Urinary Kallidinogenase
- Use of ACE inhibitor drugs within 5 half-lives before or during the study
- Stent surgery after AIS onset or planned interventional therapy
- Pregnancy, lactation, or planned pregnancy
- Life expectancy less than 3 months or unable to complete the study
- Unwillingness to be followed up or poor compliance
- Current participation in other clinical research
- AIS caused by other conditions such as dissection, vasculitis, pre-thrombotic lesions, or drug abuse
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Zhongling Zhang
Harbin, Heilongjiang, China, 150001
Actively Recruiting
Research Team
Z
Zhongling Zhang
CONTACT
S
shanshan yang
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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