Actively Recruiting

Phase Not Applicable
Age: 5Years - 21Years
All Genders
NCT06881407

Effect of a Humanoid Robot With Virtual Reality Games to Train Arm Function in Children With Cerebral Palsy - THRIVE Trial

Led by Georgia State University · Updated on 2025-03-18

42

Participants Needed

1

Research Sites

131 weeks

Total Duration

On this page

Sponsors

G

Georgia State University

Lead Sponsor

O

Ohio State University

Collaborating Sponsor

AI-Summary

What this Trial Is About

About 60% of children with cerebral palsy (CP) have impaired arm function. Improving arm function requires hundreds of repetitions per day, which is impossible in a single clinical visit. Thus, therapeutic exercises should be sustained in the home environment; however, the compliance in performing home exercise is low due to poor motivation, boredom, and forgetfulness. A better home program is needed. The objective of this project is to examine the effect of our developed "THRIVE" system (Therapeutic Humanoid Robot In Virtual Environment: the combination of robot with virtual reality games), which can provide a motivating and tailored upper-extremity intervention program with instant feedback, to improve arm function in children with CP at their home. The investigators believe the newly developed "THRIVE" system can increase children's engagement and motivation in home exercises as the robot is their playmate to demonstrate and correct their movements. The investigators will also interview parents and children with CP to understand their impression of using technology at home to shape the intervention. The expected outcome is that children with CP receiving "THRIVE" will improve their arm function more and have better engagement than those who receive VR alone immediately after intervention and at follow-up. The long-term goal is to have the "THRIVE" system be the optimal home exercise platform as it can provide challenging but motivating exercises to improve children's arm function while assisting parents in supervising their children with CP to complete home exercises.

CONDITIONS

Official Title

Effect of a Humanoid Robot With Virtual Reality Games to Train Arm Function in Children With Cerebral Palsy - THRIVE Trial

Who Can Participate

Age: 5Years - 21Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants are between the ages of 5 and 21 years
  • Diagnosed with spastic cerebral palsy
  • Manual Ability Classification System (MACS) level I-III
  • Able to sit with trunk supported
  • Able to reach forward for more than half of their arm length
  • Able to comprehend and complete three-step commands
  • Able to see a TV screen (with or without corrected vision)
  • Primary caregiver willing to follow intervention and evaluation requirements
Not Eligible

You will not qualify if you...

  • Received surgery or botulinum toxin type A injection in the training arm within the last 4 months or planned during the intervention
  • Severe attention deficit or uncontrolled epilepsy that could be triggered by video game light or sound

AI-Screening

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Trial Site Locations

Total: 1 location

1

Department of Physical Therapy, Georgia State University

Atlanta, Georgia, United States, 30302

Actively Recruiting

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Research Team

Y

Yuping Chen, ScD, PT

CONTACT

B

Bruna de Souza da Silva, BS, PT

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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