Oxygen Supplementation Effects on Breathing Recovery After General Anesthesia for Robotic-Assisted Kidney or Prostate Surgery

What this Trial Is About

Researchers are investigating how different levels of oxygen supplementation affect breathing recovery in adults after general anesthesia. This study focuses on patients undergoing robotic-assisted laparoscopic nephrectomy or prostatectomy and compares oxygen levels to see how they influence the time spent with elevated carbon dioxide in the blood, which indicates reduced ventilation. The goal is to understand if using a lower oxygen target leads to more breathing difficulties during recovery compared to a higher oxygen target. Participants will be assigned to one of two groups one receiving oxygen to maintain an oxygen saturation above 96% liberal oxygen supplementation and the other receiving oxygen to maintain saturation between 90% and 94% conservative oxygen supplementation. Oxygen levels will be carefully adjusted right after anesthesia ends and continued for 90 minutes to monitor effects on breathing. This randomized, double-blind trial builds on previous findings and aims to confirm differences in ventilation between these oxygen strategies. During the study, participants will be monitored for 90 minutes immediately after anesthesia, measuring their transcutaneous carbon dioxide levels to track breathing efficiency. Additional assessments will include breathing patterns such as apnea and hypopnea events. Researchers will use these measurements to compare how each oxygen approach influences breathing recovery. The study will follow participants until the end of the monitoring period, with safety and breathing function closely observed throughout.

The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia