Actively Recruiting

Phase Not Applicable
Age: 0Years +
All Genders
ID07109076

Effect of Immediate Skin-to-Skin Contact With the Mother on Heart Rate Variability in Newborns After Cesarean Section

Led by University Medical Centre Ljubljana · Updated on 2026-03-27

80

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying how early skin-to-skin contact affects heart rate variability (HRV) in newborns delivered by planned cesarean section and their mothers. The study focuses on the balance of the autonomic nervous system, which can be measured by HRV as an indicator of stress and physiological adaptation after birth. This randomized trial aims to see if immediate skin-to-skin contact reduces stress and improves autonomic function compared to standard care. The study involves 80 mother-newborn pairs with a gestational age of 39 weeks or more, randomly assigned to either a skin-to-skin contact group or a control group receiving routine postnatal care. In the intervention group, uninterrupted skin-to-skin contact will begin immediately after birth and last at least 15 minutes. Both groups will have maternal and neonatal electrocardiographic (ECG) monitoring for 15 minutes after birth, with additional neonatal ECG recordings at 6, 12, and 24 hours postpartum to analyze HRV. Participants will undergo ECG monitoring to assess heart rate variability measures such as RMSSD, SDNN, and pNN50 at multiple time points after birth. The study will evaluate both neonatal and maternal HRV as indicators of stress and autonomic nervous system balance. The total follow-up includes immediate post-birth monitoring and assessments up to 24 hours after birth, helping researchers understand the impact of skin-to-skin contact on neonatal adaptation following cesarean delivery.

CONDITIONS

Brief Title

Effect of Immediate Skin-to-Skin Contact on Neonatal Heart Rate Variability After Cesarean Secton

Who Can Participate

Age: 0Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Planned cesarean section
  • Gestational age of 39 weeks 0/7 or more
Not Eligible

You will not qualify if you...

  • Pregnancy complications such as hypertensive disorders or fetal growth restriction
  • Neonatal resuscitation required at birth

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - At birth and first 15 minutes postpartum

Participants undergo planned cesarean section and are assigned to either immediate skin-to-skin contact or routine postnatal care following birth.

1 visit (in-person) during delivery and immediate postpartum period

Monitoring

Duration - 24 hours after birth

Neonatal heart rate variability is monitored through ECG at 6, 12, and 24 hours after birth to assess autonomic function.

3 visits (in-person) at 6, 12, and 24 hours postpartum

Trial Site Locations

Total: 1 location

1

University Medical Center Ljubljana

Ljubljana, Ljubljana, Slovenia, 1000

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Research Team

M

Miha Lucovnik, MD, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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