Actively Recruiting
Effect of Immunonutrients on Oral Mucositis in Nasopharyngeal Carcinoma Patients After Chemoradiotherapy
Led by First Affiliated Hospital of Guangxi Medical University · Updated on 2024-08-07
190
Participants Needed
20
Research Sites
198 weeks
Total Duration
On this page
Sponsors
F
First Affiliated Hospital of Guangxi Medical University
Lead Sponsor
G
Guangdong Provincial People's Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study was to investigate the role of immunonutrion compared with standard nutrition in reducing oral mucositis in patients with locally advanced nasopharyngeal carcinoma.
CONDITIONS
Official Title
Effect of Immunonutrients on Oral Mucositis in Nasopharyngeal Carcinoma Patients After Chemoradiotherapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or non-pregnant female patients aged 18 to 70 years
- Eastern Cooperative Oncology Group (ECOG) performance status 0-1
- Pathologically confirmed non-keratinizing nasopharyngeal carcinoma (WHO type II or III)
- Newly diagnosed stage III-IVa nasopharyngeal carcinoma without metastasis
- Adequate organ function including blood counts, liver, kidney, coagulation, and cardiac enzymes
- Ability to comply with study visits, treatment, and laboratory tests
- Signed informed consent
You will not qualify if you...
- History of using Oral Impact® or ENSURE® within one month before enrollment
- Allergy or intolerance to Oral Impact®, ENSURE®, or related chemotherapy drugs
- Poor blood sugar control in diabetic patients
- Autoimmune diseases
- Active infections
- Previous radiation or anti-tumor treatments
- History of other malignant tumors
- Presence of oral mucositis at study start
- Malnutrition at study start
- Inability to eat required food amounts or need for parenteral/enteral nutrition at baseline
- Inability to eat soft solid foods at baseline
- HIV or active hepatitis B/C infection
- Participation in other intervention clinical trials within one month
- Other serious illnesses, mental health conditions, or social/family factors affecting safety or data collection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 20 locations
1
Fujian Provincial Hospital
Fuzhou, Fujian, China, 350000
Actively Recruiting
2
Fujian Cancer Hospital
Fuzhou, Fujian, China, 350014
Actively Recruiting
3
Guangdong Provincial People's Hospital
Guangzhou, Guangdong, China, 510060
Actively Recruiting
4
Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Guangzhou, Guangdong, China, 510070
Actively Recruiting
5
Huizhou Municipal Central Hospital
Huizhou, Guangdong, China, 516001
Actively Recruiting
6
The Affiliated Hospital of Guilin Medical University
Guilin, Guangxi, China, 541001
Actively Recruiting
7
Liuzhou Workers Hospital
Liuzhou, Guangxi, China, 545025
Actively Recruiting
8
The First Affiliated Hospital of Guangxi Medical University
Nanning, Guangxi, China, 530000
Actively Recruiting
9
Wuzhou Red Cross Hospital
Wuzhou, Guangxi, China, 543002
Actively Recruiting
10
First People People's Hospital of Yulin City
Yulin, Guangxi, China, 537001
Actively Recruiting
11
Red Cross Hospital of Yulin City
Yulin, Guangxi, China, 537006
Actively Recruiting
12
Huizhou Municipal Central Hospital
Haikou, Hainan, China, 570208
Actively Recruiting
13
The Second Affiliated Hospital of Hainan Medical University
Haikou, Hainan, China, 570311
Actively Recruiting
14
Hainan Cancer Hospital
Haikou, Hainan, China, 570314
Actively Recruiting
15
Second Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, China, 330000
Actively Recruiting
16
The First Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, China, 330209
Actively Recruiting
17
Qingdao Central Hospital
Qingdao, Shandong, China, 266044
Actively Recruiting
18
Zhejiang Provincial Tongde Hospital
Hangzhou, Zhejiang, China, 310012
Actively Recruiting
19
Zhejiang Provincial People's Hospital
Hangzhou, Zhejiang, China, 310014
Actively Recruiting
20
Zhejiang Cancer Hospital
Hangzhou, Zhejiang, China, 310022
Actively Recruiting
Research Team
Z
Zhen Meng, M.D
CONTACT
Y
Yating Qin, M.D
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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