Actively Recruiting

Phase Not Applicable
Age: 16Years +
All Genders
Healthy Volunteers
NCT06168162

Effect of Individualized PEEP on Postoperative Pulmonary Complication in Bariatrics

Led by Ain Shams University · Updated on 2025-02-17

50

Participants Needed

1

Research Sites

82 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Ventilation with low tidal volume and high PEEP (positive end expiratory pressure) has been shown to improve oxygenation in patients with ARDS (acute respiratory distress syndrome). In obese patients undergoing laparoscopic bariatric surgeries, the risk of postoperative pulmonary complications (PPCs) increases significantly with general anesthesia. Previous studies have shown that protective lung ventilation strategies could improve intraoperative oxygenation and lung mechanics. In this study would compare the effect of optimum individualized high PEEP versus standard PEEP - on postoperative pulmonary complications

CONDITIONS

Official Title

Effect of Individualized PEEP on Postoperative Pulmonary Complication in Bariatrics

Who Can Participate

Age: 16Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 60 years old
  • Body mass index greater than 40
  • Elective laparoscopic bariatric surgery under general anesthesia
  • ARISCAT score of 45 or higher indicating respiratory risk
Not Eligible

You will not qualify if you...

  • Previous lung surgery
  • ASA status III or IV
  • Moderate to severe obstructive or restrictive lung disease
  • Persistent intraoperative hemodynamic instability
  • Need for postoperative mechanical ventilation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Ain shams university

Cairo, Cairo Governorate, Egypt

Actively Recruiting

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Research Team

W

wessam selima, MD

CONTACT

G

ghada sharafeldin, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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