Study of Personalized High Positive End-Expiratory Pressure Versus Standard PEEP to Reduce Lung Complications After Laparoscopic Bariatric Surgery

What this Trial Is About

Researchers are studying the effects of different ventilation strategies on patients with obesity undergoing laparoscopic bariatric surgery. The study focuses on comparing an individualized high positive end-expiratory pressure PEEP approach versus a standard PEEP to see how each affects the rate of postoperative pulmonary complications within 10 days after surgery. This research is important because obesity and general anesthesia increase the risk of lung problems after surgery, and tailored ventilation may improve lung function and oxygen levels. Participants will be randomly assigned to one of two groups one receiving individualized PEEP starting at 7 cmH2O, adjusted to achieve the best static lung compliance for each patient, and the other receiving a standard PEEP of 5 cmH2O during surgery. The study is double-blinded, so neither the patients nor the researchers know which treatment is given to ensure unbiased results. During the study, pulmonary function tests will be conducted on days 1, 3, and 5 after surgery to monitor lung performance. Researchers will carefully observe participants for any lung-related complications up to 10 days post-surgery. The entire process includes preoperative assessments, surgery with assigned ventilation settings, and postoperative monitoring to evaluate outcomes and safety.

Effect of Individualized PEEP on Postoperative Pulmonary Complication in Bariatrics