Actively Recruiting
The Effect of Injectable Platelet-Rich Fibrin in Peri-implant Soft Tissue
Led by Kutahya Health Sciences University · Updated on 2025-09-11
80
Participants Needed
1
Research Sites
173 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
An inadequate amount of peri-implant soft tissue results in more plaque accumulation around the implants, peri-implant mucositis, marginal bone loss, mucosal recession, and/or attachment loss. In the literature, there are studies evaluating the application of injectable platelet-rich fibrin to the gingiva and oral mucosa around teeth, but injectable platelet-rich fibrin application around implants has not been encountered. This study aimed to evaluate the effect of subgingival and submucosal application of injectable platelet-rich fibrin on peri-implant soft tissue phenotype in patients with inadequate peri-implant soft tissue phenotype.The study will include 80 systemically healthy and non-smoking patients/implants older than 18 years of age with insufficient peri-implant keratinized mucosa width and mucosal thickness who applied to Kütahya University of Health Sciences, Faculty of Dentistry, Department of Periodontology. There are two study groups according to peri-implant mucosa phenotype: Thin phenotype and thick phenotype. All patients will undergo the same procedure of injectable platelet-rich fibrin application
CONDITIONS
Official Title
The Effect of Injectable Platelet-Rich Fibrin in Peri-implant Soft Tissue
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be over 18 years old
- Have no systemic disease
- Smoke fewer than 10 cigarettes per day or do not smoke
- Have peri-implant keratinized mucosa width less than 2 mm
- Have peri-implant mucosal thickness less than 2 mm
You will not qualify if you...
- Be outside the defined age group
- Have any systemic contraindication for periodontal surgery
- Smoke more than 10 cigarettes per day
- Have adequate peri-implant keratinized mucosa width and mucosal thickness
- Be pregnant
- Take medication that suppresses the immune system or impairs healing
- Take medication that impairs bleeding conditions
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Kütahya Health Sciences University Faculty of Dentistry
Kütahya, Turkey (Türkiye), 43100
Actively Recruiting
Research Team
B
Berceste Güler Ayyıldız
CONTACT
S
Seyma Eken
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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