Actively Recruiting
Effect of Intermittent and Continuous Theta Burst Stimulation on Sleep, Daytime Sleepiness, and Fatigue in Depression
Led by Jakub Antczak · Updated on 2024-10-15
90
Participants Needed
1
Research Sites
154 weeks
Total Duration
On this page
Sponsors
J
Jakub Antczak
Lead Sponsor
I
Institute of Psychiatry and Neurology, Warsaw
Collaborating Sponsor
AI-Summary
What this Trial Is About
Intermittent and continuous theta-burst stimulation (iTBS and cTBS respectively) are the newer modalities of transcranial magnetic stimulation with documented efficacy in treatment of depressed mood but with conflicting results regarding their efficacy in treatment of other symptoms of depression such as insomnia, daytime sleepiness and fatigue. This study will investigate the efficacy of iTBS over the left dorsolateral prefrontal cortex (DLPFC) and cTBS over the right DLPFC, compared to sham stimulation, in treatment of insomnia, daytime sleepiness and fatigue in depression.
CONDITIONS
Official Title
Effect of Intermittent and Continuous Theta Burst Stimulation on Sleep, Daytime Sleepiness, and Fatigue in Depression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Moderate or severe depressive episode without psychotic symptoms
- Diagnosis of major depression (F33.1 or F33.2) or bipolar disorder (F31.3 or F31.4)
- Athens Insomnia Scale score of five or more
- Antidepressant medication unchanged for at least one month before joining the study
You will not qualify if you...
- Contraindications to transcranial magnetic stimulation such as ferromagnetic elements in the head, pregnancy, or epilepsy
- Presence of psychotic symptoms at the time of joining
- Suicidal thoughts or attempts within three months before joining the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Institute of Psychiatry and Neurology
Warsaw, Poland, 02957
Actively Recruiting
Research Team
B
Bogdan Stefanowski, MD
CONTACT
J
Jakub Antczak, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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