Actively Recruiting
The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA
Led by VA Office of Research and Development · Updated on 2026-04-24
28
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The term "Overlap Syndrome" (OS) is used to describe the presence of both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) in a single patient. Due to premature aging, patients with OS are prone to developing functional decline up to 20 years earlier than the general population. The International Classification of Functioning, Disability and Health (ICF) evaluates functional status in chronic pulmonary disease globally in 5 domains. The investigators propose to study validated outcomes in 3 of these domains: 1) participation in life situations; 2) physical activity; and 3) cardiovascular health. The investigators long-term goal is to develop an exercise strategy tailored to Veterans with OS which will reduce the risk of functional decline through increased PA.
CONDITIONS
Official Title
The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of both COPD and obstructive sleep apnea (Overlap Syndrome) confirmed by lung function tests and sleep studies
- Montreal Cognitive Assessment (MoCA) score greater than 20
You will not qualify if you...
- History of coronary artery disease including CABG, positive stress test, infarction, or angina
- Orthopedic problems causing joint pain that limit walking
- More than two falls in the past month
- Hospitalization in the past month
- Use of daytime home oxygen
- Participation in structured exercise exceeding one hour of moderate or any strenuous activity weekly
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Salem VA Medical Center, Salem, VA
Salem, Virginia, United States, 24153-6404
Actively Recruiting
Research Team
M
Madalina Macrea, MD PhD
CONTACT
K
Kimberly L Birkett, MPH BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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