Actively Recruiting

Phase Not Applicable
Age: 3Years - 6Years
All Genders
NCT07523438

Effect of Intranasal Dexmedetomidine on the Incidence of Emergence Agitation in Children Undergoing Strabismus Surgery

Led by Alexandria University · Updated on 2026-04-13

120

Participants Needed

1

Research Sites

39 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Dexmedetomidine is a selective a-2 adrenergic agonist that provides sedative and analgesic effects. Intranasal dexmedetomidine has a slower and gradual onset compared to intravenous injection , with low incidence of nasal discomfort. Dexmedetomidine was tested at various doses and modes of administration, as well as different types of surgery and co-anesthetic drugs, as a single injection or continuous infusion. The authors have not agreed on the ideal clinical dose. The hypothesis is that intranasal dexmedetomidine 3mcg /kg will decrease the incidence of emergence agitation after strabismus surgery than dexmedetomidine 2 mcg/kg

CONDITIONS

Official Title

Effect of Intranasal Dexmedetomidine on the Incidence of Emergence Agitation in Children Undergoing Strabismus Surgery

Who Can Participate

Age: 3Years - 6Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age: 3-6 years, both sexes
  • ASA physical status class I , II.
Not Eligible

You will not qualify if you...

  • history of neurological and psychiatric disease
  • body mass index > 20 kg m-2
  • allergy to dexmedetomidine
  • patients on medical treatment which has any sedative effect
  • mentally retarded children

AI-Screening

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Trial Site Locations

Total: 1 location

1

Alexandria University

Alexandria, Egypt

Actively Recruiting

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Research Team

S

sarah m elgamal, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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