Actively Recruiting
Effect of Intranasal Oxytocin on Emotion Recognition and Acute Psycho-Social Stress-induced Cortisol Increase in Patients With Central Diabetes Insipidus and Healthy Controls
Led by University Hospital, Basel, Switzerland · Updated on 2025-05-23
42
Participants Needed
1
Research Sites
89 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to investigate the potential beneficial effects of intranasal oxytocin compared to placebo on emotion recognition and acute psychosocial stress in patients with arginine vasopressin deficiency compared to matched healthy controls.
CONDITIONS
Official Title
Effect of Intranasal Oxytocin on Emotion Recognition and Acute Psycho-Social Stress-induced Cortisol Increase in Patients With Central Diabetes Insipidus and Healthy Controls
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult healthy volunteers matched for age, sex, BMI, and hormonal status to patients
- No medication except hormonal contraception for healthy controls
- Adult patients with confirmed arginine vasopressin deficiency
- Stable hormone replacement therapy with desmopressin for at least three months
- If anterior pituitary deficiencies exist, stable substitution therapies
You will not qualify if you...
- Participation in a trial with investigational drugs within 30 days
- Active substance use disorder within the last six months
- Consumption of more than 15 alcoholic drinks per week
- Current or previous psychotic disorder such as schizophrenia spectrum
- Pregnancy or breastfeeding within the last eight weeks
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital Basel
Basel, Switzerland, 4031
Actively Recruiting
Research Team
M
Mirjam Christ-Crain, Prof. Dr.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
4
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