Actively Recruiting
Effect of Liberal and Restrictive IV Fluids on Recovery After Gallbladder Surgery
Led by King Edward Medical University · Updated on 2026-03-23
380
Participants Needed
1
Research Sites
34 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn whether giving less intravenous (IV) fluid (restrictive administration) after surgery is as effective as giving more IV fluid (liberal administration) in maintaining body stability (homeostasis) among adults undergoing laparoscopic gallbladder removal (cholecystectomy). The main questions it aims to answer are: Does restrictive IV fluid administration maintain stable blood pressure, heart rate, and urine output after laparoscopic cholecystectomy? Are there any differences in postoperative recovery or complications between restrictive and liberal fluid regimens? Researchers will compare patients receiving liberal IV fluid administration with those receiving restrictive IV fluid administration to see if both methods maintain similar postoperative homeostasis and recovery outcomes. Participants will: Be adults aged 18-60 years (ASA class I-II) undergoing elective laparoscopic cholecystectomy. Be randomly assigned to one of two groups: Group A: Liberal IV fluid administration for 6 hours after surgery. Group B: Restrictive IV fluid administration for 6 hours after surgery. Have their vital signs (pulse, blood pressure, mean arterial pressure) and urine output recorded at multiple time points after surgery (immediate, 3, 6, 12, and 24 hours).
CONDITIONS
Official Title
Effect of Liberal and Restrictive IV Fluids on Recovery After Gallbladder Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients undergoing elective cholecystectomy
- Age between 18 and 60 years
- All genders
- ASA class 1 or 2
You will not qualify if you...
- History of previous laparotomy
- Perforated gallbladder
- Surgery lasting more than 3 hours
- More than 100ml blood loss during surgery
AI-Screening
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Trial Site Locations
Total: 1 location
1
King Edward Medical University Lahore / Mayo Hospital Lahore
Lahore, Punjab Province, Pakistan, 54000
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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