Actively Recruiting

Phase 1
Age: 18Years - 60Years
All Genders
NCT07488078

Effect of Liberal and Restrictive IV Fluids on Recovery After Gallbladder Surgery

Led by King Edward Medical University · Updated on 2026-03-23

380

Participants Needed

1

Research Sites

34 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn whether giving less intravenous (IV) fluid (restrictive administration) after surgery is as effective as giving more IV fluid (liberal administration) in maintaining body stability (homeostasis) among adults undergoing laparoscopic gallbladder removal (cholecystectomy). The main questions it aims to answer are: Does restrictive IV fluid administration maintain stable blood pressure, heart rate, and urine output after laparoscopic cholecystectomy? Are there any differences in postoperative recovery or complications between restrictive and liberal fluid regimens? Researchers will compare patients receiving liberal IV fluid administration with those receiving restrictive IV fluid administration to see if both methods maintain similar postoperative homeostasis and recovery outcomes. Participants will: Be adults aged 18-60 years (ASA class I-II) undergoing elective laparoscopic cholecystectomy. Be randomly assigned to one of two groups: Group A: Liberal IV fluid administration for 6 hours after surgery. Group B: Restrictive IV fluid administration for 6 hours after surgery. Have their vital signs (pulse, blood pressure, mean arterial pressure) and urine output recorded at multiple time points after surgery (immediate, 3, 6, 12, and 24 hours).

CONDITIONS

Official Title

Effect of Liberal and Restrictive IV Fluids on Recovery After Gallbladder Surgery

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients undergoing elective cholecystectomy
  • Age between 18 and 60 years
  • All genders
  • ASA class 1 or 2
Not Eligible

You will not qualify if you...

  • History of previous laparotomy
  • Perforated gallbladder
  • Surgery lasting more than 3 hours
  • More than 100ml blood loss during surgery

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

King Edward Medical University Lahore / Mayo Hospital Lahore

Lahore, Punjab Province, Pakistan, 54000

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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