Effect of Liberal Versus Restrictive Intravenous Fluid Administration on Postoperative Homeostasis in Patients Undergoing Laparoscopic Cholecystectomy

What this Trial Is About

Researchers are evaluating whether giving less intravenous (IV) fluid after surgery is as effective as giving more IV fluid in maintaining stable body functions among adults undergoing laparoscopic gallbladder removal (cholecystectomy). This study focuses on comparing restrictive versus liberal IV fluid administration to see how well both methods maintain vital signs such as blood pressure, heart rate, and urine output, as well as their impact on postoperative recovery and complications. Participants are randomly assigned to one of two groups after surgery: one group receives 1000ml of IV fluid (liberal administration) over 6 hours, and the other receives 500ml of IV fluid (restrictive administration) over the same period. These treatments are given perioperatively, meaning around the time of surgery, to evaluate differences in maintaining postoperative homeostasis. During the study, participants will have their vital signs—including pulse, blood pressure, and mean arterial pressure—monitored at multiple times after surgery: immediately, and at 3, 6, 12, and 24 hours. Urine output will also be recorded. The main outcome measured is mean systolic blood pressure on the first day after surgery, with additional monitoring of pulse rate, diastolic blood pressure, and pulse pressure. The total participation period covers the recovery phase following laparoscopic cholecystectomy.

Effect of Liberal and Restrictive IV Fluids on Recovery After Gallbladder Surgery